Publications

The following list contains publications of earlier projects. Many of these projects are still in progress.

Click a publication's title to find the abstract on PubMed.

2010:

• Ly, L.V., Baghat, A., Versluis, M., Jordanova, E.S., Van Rooijen, N., Van Hall, T., Van der Velden, P.A., Jager, M.J. , 2010. In aged mice, outgrowth of intraocular melanoma depends on pro-angionic M2 type macrophages. J. Immunol.. vol. in press. (#563)



• Ishida, W., Fukuda, K., Kajisako, M., Takahashi, A., Sumi, T., Van Rooijen, N., Fukushima, A. , 2010. Conjunctival macrophages act as antigen-presenting cells in the conjunctiva during the development of experimental allergic conjunctivitis. Mol. Vision. vol. 16. pp. 1280-1285. (#562)



• Arnold, l., Kumar Tyagi, R., Mejia, P., Van Rooijen, N., Perignon, J.L., Druilhe, P. , 2010. Analysis of innate defences against Plasmodium falciparum in immunodeficient mice. Malar. J.. vol. in press. (#561)



• Steel, C.D., Kim, W.K., Sanford, L.D., Wellman, L.L., Burnett, S., Van Rooijen, N., Ciavarra, R.P. , 2010. Distinct macrophage subpopulations regulate viral encephalitis but not viral clearance in the CNS. J. Neuroimmunol.. vol. in press. (#560)



• Villaran, R.F., Espinosa-Oliva, A.M., Sarmiento, M., de Pablos, R.M., Arguelles, S., Delgado-Cortes, M.J., Sobrino, V., van Rooijen, N., Venero, J.L., Herrera, A.J., Cano. J., Machado, A., 2010. Ulcerative colitis exacerbates LPS-induced damage to the nigral dopaminergic system: Potential risk factor in Parkinson’s disease. J. Neurochem.. vol. in press. (#559)



• Hylton, D.J., Hoffman, S.M., Van Rooijen, N., Tomlinson, S., Fleming, S.D. , 2010. Macrophage produced IL-12p70 mediates hemorrhage-induced damage in a complement dependent manner. Shock. vol. in press. (#558)



• Alba, R., Bradshaw, A.C., Coughlan, L., Denby, L., McDonald, R.A., Waddington, S.N., Buckley, S.M., Greig, J.A., Parker, A.L., Miller, A.M., Wang, H., Lieber, A., Van Rooijen, N., McVey, J.H., Nicklin, S.A., Baker, A.H. , 2010. Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood. vol. in press. (#557)



• Stritzker, J., Weibel, S., Seubert, C., Gotz, A., Tresch, A., Van Rooijen, N., Oelschlaeger, T.A., Hill, P.J., Gentschev, I., Szalay, A.A. , 2010. Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility. Int. J. Med. Microbiol.. vol. in press. (#556)



• Garcia, M.R., Ledgerwood, L., Yang, Y., Xu, J., Lal, G., Burrell, B., Ma, G., Hashimoto, D., Li, Y., Boros, P., Grisotto, M., Van Rooijen, N., Matesanz, R., Tacke, F., Ginhoux, F., Ding, Y., Chen, S-H., Randolph, G., Merad, M., Bromberg, J.S., Ochando, J.C. , 2010. Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J. Clin. Invest. . vol. in press. (#555)



• Sutherland, M.K., Yu, C., Anderson, M., Zeng, W., Van Rooijen, N., Sievers, E.L., Grewal, I.S., Law, C.L., 2010. 5-Azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia. MAbs. vol. in press. (#554)



• Tate, M.D., Pickett, D.L., Van Rooijen, N., Brooks, A.G., Reading, P.C. , 2010. The critical role of airway macrophages in modulating disease severety during influenza virus infection of mice. J. Virol.. vol. in press. (#553)



• Mitchell, A.J., Pradel, L.C., Chasson, L., Van Rooijen, N., Grau, G.E., Hunt, N.H., Chimini, G. , 2010. Autofluorescence as a tool for myeloid cell analysis. J. Leuk. Biol.. vol. in press. (#552)



• Schmaderer, C., Eissler, R., Seibel, S., Van Rooijen, N, Baumann, M. , 2010. Blood pressure control: A facelift for macrophages? . Hypertension. vol. in press.. (#551)



• Ellett, J.D., Atkinson, C., Evans, Z.P., Amani, Z., Balish, E., Schmidt, M.G., Van Rooijen, N., Schnellmann, R.G., Chavin, K.D. , 2010. Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10. J. Immunol.. vol. 184. pp. 5849-5858. (#550)



• Barral, P., Polzella, P., Bruckbauer, A., Van Rooijen, N., Besra, G.S., Cerundolo, V., Batista, F.D. , 2010. CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes. Nature Immunology. vol. 11. pp. 303-312. (#549)



• Ianotti, C.A., Clark, M., Horn, K.P., Van Rooijen, N., Silver, J., Steinmetz, M.P. , 2010. A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI. Exp. Neurol.. vol. in press. (#548)



• Cockburn, I.A., Chen, Y-C. Overstreet, M.G., Lees, J.R., Van Rooijen, N., Farber, D.L., Zavala, F., 2010. Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. PLoS Pathog.. vol. 6(5). pp. e1000877. (#547)



• McGill, J., Van Rooijen, N., Legge, K.L. , 2010. IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. J. Exp. Med.. vol. 207. pp. 521-534. (#546)



• Unoki, N., Murakami, T., Nishijima, K., Ogino, K., Van Rooijen, N., Yoshimura, N. , 2010. SDF-1/CXCR4 contributes to the activation of tip cells and microglia in retinal angiogenesis. Invest. Ophthalmol. Vis. Res. . vol. in press. (#545)



• Catron, D.M., Pape, K.A., Fife, B.T., Van Rooijen, N., Jenkins, M.K., 2010. A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens. J. Immunol.. vol. 184. pp. 3609-3617. (#544)



• Lang, P.A., Recher, M., Honke, N., Scheu, S., Borkens, S., Gailus, N., Krings, C., Meryk, A., Kulawik, A., Cervantes-Barragan, L., Van Rooijen, N., Kalinke, U., Ludewig, B., Hengartner, H., Harris, N., Haussinger, D., Ohashi, P.S., Zinkernagel, R.M., Lang, K.S. , 2010. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-1-dependent manner in mice. Hepatology. vol. 52. pp. 25-32. (#543)



• Carlos, C.P., Mendes, G.E.F., Miquelin, A.R., Luz, M.A.M., da Silva, C.G.A., Van Rooijen, N., Coimbra, T.M., Burdmann, E.A. , 2010. Macrophage depletion attenuates chronic cyclosporine A nephrotoxicity. Transplantation. vol. 89. pp. 1362-1370. (#542)



• Godbout, C., Bilodeau, R., Van Rooijen, N., Bouchard, P., Frenette, J. , 2010. Transient neutropenia increases macrophage accumulation and cell proliferation but does not improve repair following intratendinous rupture of Achilles tendon. J. Orthop. Res.. vol. 28. pp. 1084-1091. (#541)



• Lauro, C., Cipriani, R., Catalano, M., Trettel, F., Chece, G., Brusadin, V., Antonilli, L., Van Rooijen, N., Eusebi, F., Fredholm, B.B., Limatola, C. , 2010. Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death. Neuropsychopharmacology. vol. in press. (#540)



• Lee, W-Y., Moriarty, T.J., Wong, C., Zhou, H., Strieter, R.M., Van Rooijen, N., Chaconas, G., Kubes, P. , 2010. An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nature Immunology. vol. 11. pp. 295-302. (#539)



• Triantafyllopoulou, A., Franzke, C-W., Seshan, S.V., Perino, G., Kalliolias, G.D., Ramanujam, M., Van Rooijen, N., Davidson, A., Ivashkiv, L.B. , 2010. Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages. Proc. Natl. Acad. Sci. USA. vol. 107. pp. 3012-3017. (#538)



• Stienstra, S., Saudale, F., Duval, C., Keshtkar, S., Groener, J.E., Van Rooijen, N., Staels, B., Kersten, S., Muller, M. , 2010. Kupffer cells promote hepatic steatosis via interleukin-1 beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology. vol. 51. pp. 511-522. (#537)



• Carmichael, M.D., Davis, J.M., Murphy, E.A., Carson, J.A., Van Rooijen, N., Mayer, E., Ghaffar, A. , 2010. Role of brain macrophages on IL-1 beta and fatigue following eccentric exercise-induced muscle damage. Brain Behav. Immun.. vol. 24. pp. 564-568. (#536)



• Kremer, M., Thomas, E., Milton, R.J., Perry, A.W., Van Rooijen, N., Wheeler, M.D., Zacks, S., Fried, M., Rippe. R.A., Hines, I.N. , 2010. Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. Hepatology. vol. 51. pp. 130-141. (#535)



• Simon, I.D., Van Rooijen, N., Rose J.K. , 2010. Vesicular stomatitis virus genomic RNA persists in vivo in the absence of viral replication. J. Virol.. vol. 84. pp. 3280-3286. (#534)



• Hunter, M.M., Wang, A., Parhar, K.S., Johnston, M.J.G., Van Rooijen, N., Beck, P.L., McKay, D.M., 2010. In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice. Gastroenterology. vol. 138. pp. 1395-1405. (#533)



• Machnik, A., Dahlmann, A., Kopp, C., Goss, J., Wagner, H., Van Rooijen, N., Eckardt, K-U., Muller, D.N., Park, J-K., Luft, F.C., Kerjaschki, D., Titze, J. , 2010. Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive binding protein / vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension. vol. 55. pp. 755-761. (#531)



• Reyes, J.L., Terrazas, C.A., Alonso-Trujillo, J., Van Rooijen, N., Satoskar, A.R., Terrazas, L.I. , 2010. Early removal of alternatively activated macrophages leads to Taenia crassiceps cysticercosis clearnce in vivo. Int. J. Parasitol.. vol. 40. pp. 731-742. (#530)



• De Cesare, M., Sfondrini, L., Campiglio, M., Sommariva, M., Bianchi, F., Perego, P., Van Rooijen, N., Supino, R., Rumio, C., Zunino, F., Pratesi, G., Tagliabue, E., Balsari, A. , 2010. Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN. J. Immunotherapy. vol. 33. pp. 8-15. (#528)



• Meng, Y., Beckett, M.A., Liang, H., Mauceri, H.J., Van Rooijen, N., Cohen, K., Weichselbaum, R.R. , 2010. Blockade of TNFalpha signaling in tumor-associated macrophages: A new radiosensitizing strategy. Cancer Res.. vol. 70. pp. 1534-1543. (#526)



• Hazlett, L.D., McClellan, S.A., Barrettt, R.P., Huang, X., Zhang, Y., Wu, M., Van Rooijen, N., Szliter, E. , 2010. IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas auruginosa keratitis. Invest. Ophthalmol. Vis. Res.. vol. 51. pp. 1524-1532. (#525)



• Serrats, J., Schiltz, J.C., Garcia-Bueno, B., Van Rooijen, N., Reyes, T.M., Sawchenko, P.E. , 2010. Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron. vol. 65. pp. 94-106. (#523)



• Lanthier, N.L., Molendi-Coste, O., Horsmans, Y., Van Rooijen, N., Cani, P.D., Leclercq, I.A. , 2010. Kupffer cell activation is a causal factor for hepatic insulin resistance. Am. J. Physiol.. vol. 298. pp. G107-G116. (#522)



• Van Weering H.R.J., Vinet, J., Brouwer, N., De Haas, A.L., Van Rooijen, N., Boddeke, H.W.G.M., Biber, K.P.H. , 2010. CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus. Hippocampus. vol. in press.. (#521)



• Mooney, J.E., Rolfe, B.E., Osborne, G.W., Sester, D.P., Van Rooijen, N., Campbell, G.R., Hume, D.A., Campbell, J.H. , 2010. Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. Am. J. Pathol.. vol. 176. pp. 369-380. (#516)



• Luo, J-M., Geng, Y-Q., Zhi, Y., Zhang, M-Z., Van Rooijen, N., Cui, Q. , 2010. Increased intrinsic neuronal vulnerability and decreased beneficial reaction of macrophages on axonal regeneration in aged rats. Neurobiol. Aging. vol. 31. pp. 1003-1009. (#459)



• Van Rooijen, N., Hendrikx, E. , 2010. Liposomes for specific depletion of macrophages from organs and tissues. Methods Mol. Biol. . vol. 605. pp. 189-203. (#456)

2009:

• Ritz, E., Krum, H., Schlaich, M., Whitbourn, R., Sobotka, P.A., Sadowski, J., Bartus, K., Kapelak, B., Walton, A., Sievert, H., Thambar, S., Abraham, W.T., Esler, M., Wang, Y., Tsun, Z., Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Muller, D.N., Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., Van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C., Kerjaschki, D., Titze, J. , 2009. New approaches to pathogenesis and management of hypertension. Clin. J. Am. Soc. Nephrol.. vol. 4. pp. 1886-1891. (#532)



• Zecher, D., Van Rooijen, N., Rothstein, D.M., Shlomchik, W.D., Lakkis, F.G. , 2009. An innate immune response to allogeneic nonself mediated by monocytes. J. Immunol.. vol. 183. pp. 7810-7816. (#527)



• Kolaczkowska, E., Goldys, A., Kozakiewicz, E., Lelito, M., Plytycz, B., Van Rooijen, N., Arnold, B. , 2009. Resident peritoneal macrophages and mast cells are important cellular sites of COX-1 and COX-2 activity during acute peritoneal inflammation. Arch. Immunol. Ther. Exp.. vol. 57. pp. 459-466. (#524)



• Koh, A.Y., Priebe, G.P., Ray, C., Van Rooijen, N., Pier, G.B. , 2009. Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia. Infect. Immun. . vol. 77. pp. 5300-5310. (#520)



• Chung, E-S., Chauhan, S.K., Jin, Y., Nakao, S., Hafezi-Moghadam, A., Van Rooijen, N., Zhang, Q., Chen, L., Dana, R., 2009. Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands. Am. J. Pathol.. vol. 175. pp. 1984-1992. (#519)



• Ghulam Muhammad, A.K., Candolfi, M., King, G.D., Yagiz, K., Foulad, D., Mineharu, Y., Kroeger, K.M., Treuer, K.A., Nichols, W.S., Sanderson, N.S., Yang, J., Khayznikov, M., Van Rooijen, N., Lowenstein, P.R., Castro, M.G. , 2009. Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clin. Cancer Res.. vol. 15. pp. 6113-6127. (#518)



• Bedoret, D., Wallemacq, H., Marichal, T., Desmet, C., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B., Thielen, C., Gustin, P., De Leval, L., Van Rooijen, N., Le Moine, A., Vanderplasschen, A., Cataldo, D., Drion, P-V., Moser, M., Lekeux, P., Bureau, F. , 2009. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice . J. Clin. Invest. . vol. 119. pp. 3723-3738. (#517)



• Zhao, J., Zhao, J., Van Rooijen, N., Perlman, S. , 2009. Evasion by stealth: Inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice. PLoS Pathog.. vol. 5(10). pp. e 1000636. (#515)



• Kurowska-Stolarska, M., Kewin, P., Stolarski, B., Murphy, G., Ying, S., Pitman, N., Mirchandani,A., Rana, B., Van Rooijen, N., McSharry, C., Shepherd, M., McInnes,I.B., Xu, D., Liew, F.Y., 2009. IL-33 amplifies alternatively-activated macrophages that contribute to airway inflammation. J. Immunol.. vol. 183. pp. 6469-6477. (#514)



• McKee, A.S., Munks, M.W., MacLeod, M.K.L., Fleenor, C.J., Van Rooijen, N., Kappler, J.W., Marrack, P. , 2009. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J. Immunol.. vol. 183. pp. 4403-4414. (#513)



• Gyorki, D.E., Asselin-Labat, M-L., Van Rooijen, N., Lindeman, G.L., Visvader, J.E. , 2009. Resident macrophages influence stem cell activity in the mammary gland. Breast Canc. Res. . vol. 11. pp. R62. (#512)



• Clementi, A.H., Gaudy, A.M., Van Rooijen, N., Pierce, R.H., Mooney, R.A., 2009. Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 Signaling, and further decreases in insulin signaling. Bioch. Bioph. Acta. vol. 1792. pp. 1062-1072. (#511)



• Larsson, C., Lundqvist, J., Van Rooijen, N., Bergstrom, S. , 2009. A novel animal model of Borrelia recurrentis louse-borne relapsing fever borreliosis using immunodeficient mice. Plos Neglected Trop. Dis. . vol. 3(9). pp. e522. (#510)



• Holub, M., Cheng, C-W., Mott, S., Wintermeyer, P., Van Rooijen, N., Gregory, S.H. , 2009. Neutrophils sequestered in the liver suppress the proinflammatory response of Kupffer cells to systemic bacterial infection. J. Immunol.. vol. 183. pp. 3309-3316. (#509)



• Majeti, R., Chao, M.P., Alizadeh, A.A., Pang, W.W., Jaiswal, S., Gibbs Jr., K.D., Van Rooijen, N., Weissmman, I.L. , 2009. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell. vol. 138. pp. 286-299. (#508)



• Lee, P.Y., Li, Y., Kumagai, Y., Xu, Y.,Weinstein, J.S., Kellner, E.S., Nacionales, D.C., Butfiloski, E.J., Van Rooijen, N., Akira, S., Sobel, E.S., Satoh, M., Reeves, W.H., 2009. Type-1 interferon modulates monocyte recruitment and maturation in chronic inflammation. Am. J. Pathol.. vol. 175. pp. 2023-2033. (#507)



• Fink, K., Ng, C., Nkenfou, C., Vasudevan, S., Van Rooijen, N., Schul, W. , 2009. Depletion of macrophages in mice results in higher dengue virus titers and highlights the rol of macrophages for virus control. Eur. J. Immunol.. vol. 39. pp. 2809-2821. (#506)



• Mircescu, M.M., Lipuma, L., Van Rooijen, N., Pamer, E.G., Hohl, T.M. , 2009. Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection. J. Infect. Dis. vol. 200. pp. 647-656. (#505)



• Ye, Z., Kerschen, E.J., Cohen, D.A., Kaplan, A.M., Van Rooijen, N., Straley, S.C. , 2009. Gr1+ cells control growth of YopM-negative Yersinia pestis during systemic plague. Infect. Immun. . vol. 77. pp. 3791-3806. (#504)



• Markovic, D.S., Vinnakota, K., Chirasani, S., Synowitz, M., Wisniewski, P., Lehmann, S., Kalin, R., Van Rooijen, N., Holmbeck, K., Heppner, F.L., Kiwit, J., Lehnardt, S., Kaminska, B., Glass, R., Kettenmann, H. , 2009. Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proc. Natl. Acad. Sci. USA. vol. 106. pp. 12530-12535. (#503)



• Betting, D.J., Yamada, R.E., Kafi, K., Said, J., Van Rooijen, N., Timmerman, J.M. , 2009. Intratumoral but not systemic delivery of CpG oligodeoxynucleotide augments the efficacy of anti-CD20 monoclonal antibody therapy against B cell lymphoma. J. Immunotherapy. vol. 32. pp. 622-631. (#502)



• Ashley, S.L., Welton, A.R., Harwood, K.M., Van Rooijen, N., Spindler, K.R. , 2009. Mouse adenovirus type 1 infection of macrophages. Virology. vol. 390. pp. 307-314. (#501)



• Kirby, A.C., Beattie, L., Maroof, A., Van Rooijen, N., Kaye, P.M., 2009. SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis following L. donovani-induced loss of marginal zone macrophages. Am. J. Pathol.. vol. 175. pp. 1107-1115. (#500)



• Wernli, G., Hasan, W., Bhattacherjee, A., Van Rooijen, N., Smith, P.G. , 2009. Macrophage depletion suppresses sympathetic hyperinnervation following myocardial infarction. Basic Res. Cardiol. . vol. 104. pp. 681-693. (#499)



• Lu, P., Li, L., Liu, G., Van Rooijen, N., Mukaida, N., Zhang, X. , 2009. Opposite roles of CCR2 and CX3CR1 macrophages in alkali-induced corneal neovascularization. Cornea. vol. 28. pp. 562-569. (#498)



• Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Muller, D.N., Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., Van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C., Kerjaschki, D., Titze, J. , 2009. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nature Medicine. vol. 15. pp. 545-552. (#497)



• Woodman, M.E., Cooley, A.E., Avdiushko, R., Bowman, A., Botto, M., Wooten, R.M., Van Rooijen, N., Cohen, D.A., Stevenson, B. , 2009. Roles for phagocytic cells and complement in controlling relapsing fever infection. J. Leuk. Biol.. vol. 86. pp. 727-736. (#496)



• Imamura, M., Tsutsui, H., Yasuda, K., Uchiyama, R., Yumikura-Futatsugi, S., Mitani, K., Hayashi, S., Akira, S., Taniguchi, S-I., Van Rooijen, N., Tschopp, J., Yamamoto, T., Fujimoto, J., Nakanishi, K. , 2009. Contribution of TIR domain-containing adapter inducing IFN beta – mediated IL-18 release to LPS-induced liver injury in mice. J. Hepatol.. vol. 51. pp. 333-341. (#495)



• Alba, R., Bradshaw, A.C., Parker, A.L., Bhella, D., Waddington, S.N., Nicklin, S.N., Van Rooijen, N., Custers, J., Goudsmit, J., Barouch, D.H., McVey, J.H., Baker, A.H. , 2009. Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: Effect of mutagenesis on FX interactions and gene transfer. Blood. vol. 114. pp. 965-971. (#494)



• Donnelly, D.J., Gensel, J.C., Ankeny, D.P., Van Rooijen, N., Popovich, P.G., 2009. An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology. J. Neurosci. Methods. vol. 181. pp. 36-44. (#493)



• Wan, H., Coppens, J.M.C., Van Helden-Meeuwsen, C.G., Leenen, P.J.M., Van Rooijen, N., Khan, N.A., Kiekens, R.C.M., Benner, R., Versnel, M.A. , 2009. Chorionic gonadotropin alleviates thioglycollate-induced peritonitis by affecting macrophage function. J. Leuk. Biol.. vol. 86. pp. 361-370. (#492)



• Perrigoue, J.G., Saenz, S.A., Siracusa, M.C., Allenspach,E.J., Taylor, B.C., Giacomin, P.R., Nair, M.G., Du, Y., Zaph, C., Van Rooijen, N., Comeau, M.R., Pearce, E.J., Laufer, T.M., Artis, D. , 2009. MHC class II-dependent basophil-CD4+ T cell interactions promote Th2 cytokine-dependent immunity. Nature Immunology. vol. 10. pp. 697-705. (#491)



• Jaiswal, S., Jamieson, C.H.M., Pang, W.W., Park, C.Y., Chao, M.P., Majeti, R., Traver, D., Van Rooijen, N., Weissman, I.L. , 2009. CD47 is up-regulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell. vol. 138. pp. 271-285. (#490)



• Cawood, R., Chen, H.H., Carroll, F., Van Rooijen, N., Bazan-Peregrino, M., Seymour, L.W. , 2009. Use of tissue-specific microRNA to control pathology of wild type adenovirus without attenuation of its ability to kill cancer cells. PLoS Pathog.. vol. 5(5). pp. e 1000440. (#489)



• Seki, E., De Minicis, S., Inokuchi, S., Taura, K., Miyai, K., Van Rooijen, N., Schwabe, R.F., Brenner, D.A. , 2009. CCR2 promotes hepatic fibrosis in mice. Hepatology. vol. 50. pp. 185-197. (#488)



• Horst, A.K., Bickert, T., Brewig, N., Ludewig, P., Van Rooijen, N., Schumacher, U., Beauchemin, N., Ito, W.D., Fleischer, B., Wagener, C., Ritter, U. , 2009. CEACAM1+ myeloid cells control angiogenesis in inflammation. Blood. vol. 113. pp. 6726-6736.. (#487)



• Gupta, R., Van Rooijen, N., Sefton, M.V. , 2009. Fate of endothelialized modular constructs implanted in an omental pouch in nude rats. Tissue Eng. Part A. vol. 15. pp. 2875-2887. (#486)



• Di Paolo, N.C., Van Rooijen, N., Shayakhmetov, D.M. , 2009. Redundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver. Mol. Ther.. vol. 17. pp. 675-684. (#485)



• Gensel, J.C., Nakamura, S., Guan, Z., Van Rooijen, N., Ankeny, D.P., Popovich, P.G. , 2009. Macrophages promote axon regeneration with concurrent neurotoxicity. J. Neuroscience. vol. 29. pp. 3956-3968. (#484)



• Redecha, P., Van Rooijen, N., Torry, D., Girardi, G. , 2009. Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury. Blood. vol. 113. pp. 4101-4109. (#483)



• Wilson, M.R., O’Dea, K.P., Zhang, D., Shearman, A.D., Van Rooijen, N., Takata, M. , 2009. Role of lung-marginated monocytes in an in vivo mouse model of ventilator induced lung injury. Am. J. Respir. Crit. Care Med. . vol. 179. pp. 914-922. (#482)



• Leendertse, M., Willems, R.J.L., Giebelen, I.A.J., Roelofs, J.J.T.H., Van Rooijen, N., Bonten, M.J.M., Van der Poll, T., 2009. Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice. Innate Immunity. vol. 15. pp. 3-12. (#481)



• Hernandez, L., Smirnova, T., Kedrin, D., Wyckoff, J., Stanley, R.E., Cox, D., Muller, W.J., Pollard, J.W., Van Rooijen, N., Segall, J.E. , 2009. The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta 1 and CXCL 12. Cancer Res.. vol. 69. pp. 3221-3227. (#480)



• Halin, S., Rudolfsson, S.H., Van Rooijen, N., Bergh, A. , 2009. Extratumoral macrophages promote tumor and vascular growth in an orthopic rat prostate tumor model. Neoplasia. vol. 11. pp. 177-186. (#479)



• Campion, S.N., Tatis-Rios, C., Augustine, L.M., Goedken, M.J., Van Rooijen, N., Cherrington, N.J., Manautou, J.E., 2009. Effect of allyl alcohol on hepatic transporter expression: Zone patterns of expression and role of Kupffer cell function. Toxicol. Appl. Pharmacol.. vol. 236. pp. 49-58. (#478)



• Zandbergen, H.R., Sharma, U.C., Gupta, S., Verjans, J.W.H., Van den Borne, S., Pokharel, S., Van Brakel, T., Duijvestijn, A., Van Rooijen, N., Maessen, J.G., Reutelingsperger, C., Pinto, Y.M., Narula, J., Hofstra, L. , 2009. Macrophage depletion in hypertensive rats accelerates development of cardiomyopathy. J. Cardiovasc. Pharmacol. Ther.. vol. 14. pp. 68-75. (#477)



• Manicone, A.M., Birkland, T.P., Betsuyaku, T., Van Rooijen, N., Lohi, J., Keski-Oja, J., Wang, Y., Skerrett, S.J., Parks, W.C. , 2009. Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas Aeruginosa pneumonia. J. Immunol.. vol. 182. pp. 3866-3876. (#476)



• Eidsmo, L., Allan, R., Caminschi, I., Van Rooijen, N., Heath, W.R., Carbone, F.R. , 2009. Differential migration of epidermal and dermal DCs during skin infection. J. Immunol.. vol. 182. pp. 3165-3172. (#475)



• Pande, K., Ueda, R., Machemer, T., Sathe, M., Tsai, V., Brin, E., Delano, M.J., Van Rooijen, N., McClanahan, T.K., Talmadge, J.E., Moldawer, L.L., Phillips, J.H., Laface, D.M. , 2009. Cancer-induced expansion and activation of CD11b(+)Gr-1(+) cells predispose mice to adenoviral-triggered anaphylactoid-type reactions. Mol. Ther.. vol. 17. pp. 508-515. (#474)



• Roychowdhury, S., McMullen, M.R., Pritchard, M.T., Hise, A.G., Van Rooijen, N., Medof, M.E., Stavitsky, A.B., Nagy, L.E. , 2009. An early complement-dependent and TLR-4 independent phase in the pathogenesis of ethanol-induced liver injury. Hepatology. vol. 49. pp. 1326-1334. (#473)



• Oflazoglu, E., Stone, I.J., Brown, L., Gordon, K.A., Van Rooijen, N., Jonas, M., Law, C.L., Grewal, I.S., Gerber, H.P., 2009. Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40. Brit. J. Cancer. vol. 100. pp. 113-117. (#471)



• Kolaczkowska, E., Grzybec, W., Van Rooijen, N., Piccard, H., Plytycz, B., Arnold, B., Opdenakker, G. , 2009. Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis. J. Leuk. Biol.. vol. 85. pp. 374-381. (#470)



• O’Dea, K.P., Wilson, M.R., Dokpesi, J.O., Wakabayashi, K., Tatton, L., Van Rooijen, N., Takata, M. , 2009. Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs towards acute injury. J. Immunol.. vol. 182. pp. 1155-1166. (#469)



• Nuki, Y., Matsumoto, M.M., Tsang, E., Young, W.L., Van Rooijen, N., Kurihara, C., Hashimoto, T. , 2009. Roles of macrophages in flow-induced outward vascular remodeling. J. Cereb. Blood Flow Metab. . vol. 29. pp. 495-503. (#468)



• Parker, A.L., Waddington, S.N., Buckley, S.M., Custers, J., Havenga, M.J., Van Rooijen, N., Goudsmit, J., McVey, J.H., Nickin, S.A., Baker, A.H. , 2009. Effect of neutralising sera on factor X-mediated adenovirus serotype 5 gene transfer. J. Virol.. vol. 83. pp. 479-483. (#467)



• Traeger, T., Kessler, W., Hilpert, A., Mikulcak, M., Entleutner, M., Koerner, P., Westerholt, A., Cziupka, K., Van Rooijen, N., Heidecke, C.D., Maier, S. , 2009. Selective depletion of alveolar macrophages in polymicrobial sepsis increases lung injury, bacterial load and mortality but does not affect cytokine release. Respiration. vol. 77. pp. 203-213. (#464)



• Wildenberg, M.E., Welzen-Coppens, J.M.C., Van Helden-Meeuwsen, C.G., Bootsma, H., Vissink, A., Van Rooijen, N., Van de Merwe, J.P., Drexhage, H.A., Versnel, M.A. , 2009. Increased frequency of CD16+ monocytes and the presence of activated dendritic cells in salivary glands in primary Sjogren’s syndrome. Ann. Rheum. Dis.. vol. 68. pp. 420-426. (#435)

2008:

• Brechot, N., Gomez, E., Bignon, M., Khallou-Laschet, J., Dussiot, M., Cazes, A., Alanio-Brechot, C., Durand,M., Philippe, J., Silvestre, J-S., Van Rooijen, N., Corvol, P., Nicoletti, A., Chazaud, B., Germain, S. , 2008. Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice. PLoS One. vol. 3(12). pp. e 3950. (#472)