Publications

The following list contains publications of earlier projects. Many of these projects are still in progress.

Click a publication's title to find the abstract on PubMed.

2012:

• Sendler, M., Dummer, A., Weiss, F.U., Kruger, B., Wartmann, T., Scharffetter-Kochanek, K., Van Rooijen, N., Malla, S.R., Aghdassi, A., Halangk, W., Lerch, M.M., Mayerle, J. , 2012. TNFalpha secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice. Gut. vol. in press.. (#658)



• Vinet, J., Van Weering, H.R.J., Heinrich, A., Kalin, R.E., Wegner, A., Brouwer, N., Heppner, F.L., Van Rooijen, N., Boddeke, H.W.G.M., Biber, K., 2012. Neuroprotective function for ramified microglia in hippocampal excitotoxicity. J. Neuroinflamm.. vol. in press.. (#657)



• Weber, S., Tian, H., Van Rooijen, N., Pirofski, L-A. , 2012. A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires FcgammaRIII and macrophages to mediate protection against pneumococcal pneumonia in mice. Infect. Immun.. vol. in press.. (#656)



• Chen, F., Liu, Z., Wu, W., Rozo, C., Bowdridge, S., Millman, A., Van Rooijen, N., Urban, Jr. J.F., Wynn, T.A., Gause, W.C. , 2012. An essential role for the Th2-type response in limiting tissue damage during helminth infection. Nature Medicine. vol. in press.. (#655)



• Anderson, A.L., Zheng, Y., Song, D.C., LaRosa, D., Van Rooijen,N., Kierstein, G., Kierstein, S., Haczku, A., Levinson, A.I. , 2012. The B-cell superantigen Finegoldia magna protein L causes pulmonary inflammation by a mechanism dependent on MyD88 but not B cells or immunoglobulins. Inflamm. Res.. vol. in press.. (#654)



• Boulter, L., Govaere, O., Bird, T.G., Radulescu, S., Ramachandran, P., Pellicoro, A., Ridgway, R.A., Seo, S.S., Spee, B., Van Rooijen, N., Sansom, O.J., Iredale, J.P., Lowell, S., Roskams, T., Forbes, S.J. , 2012. Macrophage derived Wnt signalling opposes Notch signaling in a Numb mediated manner to specify HPC fate in chronic liver disease in human and mouse. Nature Medicine. vol. in press.. (#653)



• Gliem, M., Mausberg, A.K., Lee, J-I., Simiantonakis, I., van Rooijen, N., Hartung, H-P., Jander, S. , 2012. Macrophages prevent hemorrhagic infarct transformation in murine stroke models. Ann. Neurol.. vol. in press.. (#652)



• Linde, N., Lederle, W., Depner, S., Van Rooijen, N., Gutschalk, C.M., Mueller, M.M. , 2012. Vascular endothelial growth factor induced skin carcinogenesis depends on recruitment and alternative activation of macrophages. J. Pathol.. vol. in press.. (#651)



• Mawhinney, L.A., Thawer, S.G., Van Rooijen, N., Brown, A., Weaver, L.C., Dekaban, G.A. , 2012. Differential detection and distribution of microglial and hematogenous macrophage populations in the injured spinal cord of the lys-EGFP-ki transgenic mouse. J. Neuropathol. Exp. Neurol.. vol. in press.. (#650)



• Landoni, V., Chiarella, P., Martire-Greco, D., Schierloh, P., Van Rooijen, N., Rearte, B., Palermo, M., Isturiz, M.A., Fernandez, G. , 2012. Tolerance to lipopolysaccharide promotes an enhanced neutrophil extracellular traps formation leading to a more efficient bacterial clearance in mice. Clin. Exp. Immunol.. vol. in press.. (#649)



• Garaude, J., Van Rooijen, N., Blander, J.M., 2012. Superior tumor immunotherapy by simultaneous targeting of Toll-like and Nod-like receptors. Science Translation. Med.. vol. in press.. (#648)



• Honke, N., Shaabani, N., Cadeddu, G., Sorg, U.R., Zhang, D.E., Trilling, M., Klingel, K., Sauter, M., Kandolf, R., Gailus, N., van Rooijen, N., Burkart, C., Baldus, S.E., Grusdat, M., Lohning, M., Hengel, H., Pfeffer, K., Tanaka, M., Haussinger, D., Recher, M., Lang, P.A., Lang, K.S. , 2012. Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nature Immunology. vol. 13. pp. 51-57. (#646)



• Robbins, C.S., Chudnovskiy, A., Rauch, P.J., Figueiredo, J.L., Iwamoto, Y., Gorbatov, R., Etzrodt, M., Weber, G.F., Ueno, T., van Rooijen, N., Mulligan-Kehoe, M.J., Libby, P., Nahrendorf, M., Pittet, M.J., Weissleder, R., Swirski, F.K., 2012. Extramedullary hematopoiesis generates Ly-6Chigh monocytes that infiltrate atherosclerotic lesions. Circulation. vol. in press.. (#644)



• Jonsson, F., Mancardi, D.A., Zhao, W., Kita, Y., Iannascoli, B., Khun, H., Van Rooijen, N., Shimizu, T., Schwartz, L.B., Daeron, M., Bruhns, P. , 2012. Human Fc gamma RIIA induces anaphylactic and allergic reactions. Blood. vol. in press.. (#643)



• Schwandt, T., Schumak, B., Gielen, G.H., Jungerkes, F., Schmidbauer, P., Klocke, K., Staratschek-Jox, A., van Rooijen, N., Kraal, G., Ludwig-Portugall, I., Franken, L., Wehner, S., Kalff, J.C., Weber, O., Kirschning, C., Coch, C., Kalinke, U., Wenzel, J., Kurts, C., Zawatzky, R., Holzmann, B., Layland, L., Schultze, J.L., Burgdorf, S., den Haan, J.M., Knolle, P.A., Limmer, A. , 2012. Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J.. vol. in press.. (#641)



• Drabek, T., Janata, A., Jackson, E.K., End, B., Stezoski, J., Vagni, V.A., Janesko-Feldman, K., Wilson, C.D., van Rooijen, N., Tisherman, S.A., Kochanek, P.M. , 2012. Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. Resuscitation. vol. in press. (#637)



• Ingersoll, M.A., Potteaux, S., Alvarez, D., Hutchison, S.B., Van Rooijen, N., Randolph, G.J. , 2012. Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis. Immunobiology. vol. in press.. (#631)



• Wang, C., Wang, H., Ide, K., Wang, Y., Van Rooijen, N., Ohdan, H., Yang, Y.G. , 2012. Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPalpha capable of binding to human CD47. Cell Transplant. vol. in press.. (#598)

2011:

• Gommet, C., Billecocq, A., Jouvion, G., Hasan, M., Zaverucha do Valle, T., Guillemot, L., Blanchet, C., Van Rooijen, N., Montagutelli, X., Bouloy, M., Panthier, J.J., 2011. Tissue tropism and target cells of NSs-deleted Rift Valley fever virus in live immunodeficient mice. PLoS Negl. Trop. Dis.. vol. 5(12). pp. e1421. (#647)



• Moldobaeva, A., Van Rooijen, N., Wagner, E.M. , 2011. Effects of ischemia on lung macrophages. PLoS One. vol. 6(11). pp. e26716. (#645)



• Fischer, M.A., Davies, M.L., Reider, I.E., Heipertz, E.L., Epler, M.R., Sei, J.J., Ingersoll, M.A., Van Rooijen, N., Randolph, G.J., Norbury, C.C., 2011. CD11b+ , Ly6G+ Cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog.. vol. 7(11). pp. e1002374. (#642)



• Strait, R.T., Hicks, W., Barasa, N., Mahler, A., Khodoun, M., Kohl, J., Stringer, K., Witte, D., Van Rooijen, N., Susskind, B.M., Finkelman, F.D. , 2011. MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice. J. Exp. Med.. vol. 208. pp. 2525-2544. (#640)



• Arroba, A.I., Alvarez-Lindo, N., Van Rooijen, N., de la Rosa, E.J. , 2011. Microglia-mediated IGF-I neuroprotection in the rd10 mouse model of retinitis pigmentosa. Invest. Opthalmol. Vis. Res.. vol. 52. pp. 9124-9130. (#639)



• Sakoda, Y., Anand, S., Zhao, Y., Park, J-J., Liu, Y.,Kuramasu, A., Van Rooijen, N., Chen, L., Strome, S.E., Hancock, W.W., Chen, L., Tamada, K. , 2011. Herpesvirus entry mediator regulates hypoxia-inducible factor 1 alpha and erythropoiesis in mice. J. Clin. Invest. . vol. 121. pp. 4810-4819. (#638)



• Hu, Z., Van Rooijen, N., Yang, Y-G. , 2011. Macrophages prevent human red blood cell reconstitution in immuodeficient mice. Blood. vol. 118. pp. 5938-5946. (#636)



• Quattrocchi, V., Langellotti, C., Pappalardo, J.S., Olivera, V., Di Giacomo, S., van Rooijen, N., Mongini, C., Waldner, C., Zamorano, P.I. , 2011. Role of macrophages in early protective immune responses induced by two vaccines against foot and mouth disease. Antiviral Res.. vol. 92. pp. 262-270. (#635)



• Benseler, V., Warren, A., Vo, M., Holz, L.E., Tay, S.S., Le Couteur, D.G., Breen, E., Allison, A.E., Van Rooijen, N., McGuffog, C., Schlitt, H.J., Bowen, D.G., McCaughan, G.W., Bertolino, P.J. , 2011. Hepatocyte entry leads to degradation of autoreactive CD8 T cells. Proc. Natl. Acad. Sci. USA. vol. 108. pp. 16735-16740. (#634)



• Lanthier, N., Molendi-Coste, O., Cani, P.D., Van Rooijen, N., Horsmans, Y., Leclercq, I.A., 2011. Kupffer cell depletion prevents but has no therapeutic impact on metablic and inflammatory changes induced by a high fat diet. FASEB J.. vol. 25. pp. 4301-4311. (#633)



• Feng, B., Jiao, P., Nie, Y., Kim, T., Jun, D., Van Rooijen, N., Yang, Z., Xu, H. , 2011. Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice. PLoS One. vol. 6(9). pp. e24358. (#632)



• Westwell-Roper, C., Dai, D.L., Soukhatcheva, G., Potter, K.J., Van Rooijen, N., Ehses, J.A., Verchere, C.B. , 2011. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction. J. Immunol.. vol. 187. pp. 2755-2765. (#630)



• Koneru, R., Kobiler, D., Lehrer, S., Li, J., Van Rooijen, N., Banerjee, D., Glod, J. , 2011. Macrophages play a key role in early blood brain barrier reformation after hypothermic brain injury. Neurosci. Lett. . vol. 501. pp. 148-151. (#629)



• Esplugues, E., Huber, S., Gagliani, N., Hauser, A.E., Town, T., Wan, Y.Y., O’Connor, W., Rongvaux, A., Van Rooijen, N., Habermann, A.M., Iwakura, Y., Kuchroo, V.K., Kolls, J.K., Bluestone, J.A., Herold, K.C., Flavell, R.A., 2011. Control of TH17 cells occurs in the small intestine. Nature. vol. 475. pp. 514-518. (#628)



• Mourao-Sa, D., Robinson, M.J., Zelenay, S., Sancho, D., Chakravarty, P., Larsen, R., Plantinga, M., Van Rooijen, N., Soares, M.P., Lambrecht, B., Sousa, C.R. , 2011. CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses. Eur. J. Immunol.. vol. 41. pp. 3040-3053. (#627)



• Zhao, L., Rose, K.M., Elliott, R., Van Rooijen, N., Weiss, S.R., 2011. Cell-type-specific type 1 interferon antagonism influences organ tropism of murine coronavirus. J. Virol.. vol. 85. pp. 10058-10068. (#626)



• Worthington, Z.E., Van Rooijen, N., Carbonetti, N.H. , 2011. Enhancement of Bortella parapertussis infection by Bordetella pertussis in mixed infection of the respiratory tract. FEMS Immunol. Med. Microbiol. . vol. 63. pp. 119-128. (#625)



• Van Hul, N., Lanthier, N., Espanol, R., Abarca, J., Van Rooijen, N., Dustin, M., Leclercq, I. , 2011. Kupffer cells influence parenchymal invasion and phenotypic orientation but not the proliferation of liver progenitor cells in a murine model of liver injury. Am. J. Pathol.. vol. 179. pp. 1839-1850. (#624)



• Schliehe, C., Redaelli, C., Engelhardt, S., Fehlings, M., Mueller, M., Van Rooijen, N., Thiery, M., Weller, H., Groettrup, M., 2011. CD8 - dendritic cells and macrophages cross-present PLGA particle-encapsulated antigen in vivo. J. Immunol.. vol. 187. pp. 2112-2121. (#623)



• Lee, S.M., Rosen, S., Weinstein, P., Van Rooijen, N., Noble-Haeusslein, L.J. , 2011. Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury. J. Neurotrauma. vol. 28. pp. 1893-1907. (#622)



• Shi, Y.Y., Wang, Y.S., Zhang, Z.X., Cai, Y., Zhou, J., Hou, H.Y., Van Rooijen, N. , 2011. Monocyte/macrophages promote vasculogenesis in choroidal neovascularization in mice by stimulating SDF-1 expression in RPE cells. Graef. Arch. Clin. Exp. Ophthalmol. . vol. 249. pp. 1667-1679. (#621)



• Gibbons, M.A., MacKinnon, A.C., Ramachandran, P., Duffin, R., Dhaliwal, K., Phythian-Adams, A.T., Van Rooijen, N., Haslett, C., Howie, S.E., Simpson, A.J., Hirani, N., Gauldie, J., Iredale, J.P., Sethi, T., Forbes, S.J. , 2011. Ly6Chi monocytes direct alternatively activated pro-fibrotic macrophage regulation of lung fibrosis. Am. J. Respir. Crit. Care Med. . vol. 184. pp. 569-581. (#620)



• Sitia, G., Iannacone, M., Aiolphi, R., Isogawa, M., Van Rooijen, N., Scozzesi, C., Bianchi, M.E., Von Adrian, U.H., Chisari, F.V., Guidotti, L.G. , 2011. Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. PLoS Pathog.. vol. 7(6). pp. e1002061. (#619)



• Kohler,J., Breitbach, K., Renner, C., Heitsch, A.K., Bast, A., Van Rooijen, N., Vogelgesang, S., Steinmetz, I.l, 2011. NADPH-oxidase but not inducible nitric oxide synthase contributes to resistance in a murine Staphylococcus aureus Newman pneumonia mode. Microbes Infect.. vol. 13. pp. 914-922. (#618)



• Weisser, S.B., Brugger, H.K., Voglmaier, N.S., Van Rooijen, N., Sly, L.M. , 2011. SHIP deficient alternatively activated macrophages protect mice during DSS-induced colitis. J. Leuk. Biol.. vol. 90. pp. 483-492. (#617)



• Flores-Langarica, A., Marshall, J.L., Bobat, S., Mohr, E., Hitchcock, J., Ross, E.A., Coughlan, R.E., Khan, M., Van Rooijen, N., Henderson, I.N., MacLennan, I.C.M., Cunningham, A.F. , 2011. T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella. Eur. J. Immunol.. vol. 41. pp. 2654-2665. (#616)



• Santiago-Raber, M-L., Baudino, L., Alvarez, M., Van Rooijen, N., Nimmerjahn, F., Izui, S. , 2011. TLR7/9-mediated monocytosis and maturation of Gr-1hi inflammatory monocytes towards Gr-1lo resting monocytes implicated in murine lupus. J. Autoimmun.. vol. 37. pp. 171-179. (#615)



• Jenkins, S.J., Ruckerl, D., Cook, P.C., Jones, L.H., Finkelman, F.D., Van Rooijen, N., MacDonald, A.S., Allen, J.E. , 2011. Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation. Science. vol. 332. pp. 1284-1288. (#614)



• Smirnova, T., Adomako, A., Locker, J., Van Rooijen, N., Prystowsky, M.B., Segall, J.E. , 2011. In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages. Am. J. Pathol.. vol. 178. pp. 2857-2865. (#613)



• Narasaraju, T.A., Yang, E., Samy, R.P., Ng, H.H., Poh, W.P., Liew, A.A., Phoon, M.C., Van Rooijen, N., Chow, V.T.K. , 2011. Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am. J. Pathol.. vol. 179. pp. 199-210. (#612)



• Kinloch, R.D., Lee, C-M., Van Rooijen, N., Morgan, E.T. , 2011. Selective role for tumor necrosis factor-alpha, but not interleukin-1 of Kupffer cells, in down regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen. Biochem. Pharm. . vol. 82. pp. 312-321. (#611)



• Dorr, A.D., Wilson, M.R., Wakabayashi, K., Waite, A.C., Patel, B.V., Van Rooijen, N., O’Dea, K.P., Takata, M. , 2011. Sources of alveolar soluble TNF receptors during acute lung injury of different etiologies. J. Appl. Physiol.. vol. 111. pp. 177-184. (#610)



• Cheng, C.W., Duwaerts, C.C., Van Rooijen, N., Wintermeyer, P., Mott, S., Gregory, S.H. , 2011. NK cells suppress experimental cholestaticliver injury by an interleukin-6-mediated, Kupffer cell- dependent mechanism. J. Hepatol.. vol. 54. pp. 746-752. (#609)



• Arias, K., Chu, D.K., Flader, K., Botelho, F., Walker, T., Arias, N., Humbles, A.A., Coyle, A.J., Oettgen, H.C., Chang, H-D., Van Rooijen, N., Waserman, S., Jordana, M. , 2011. Distinct immune-effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice. J. Allergy Clin. Immun. . vol. 127. pp. 1552-1561. (#608)



• McGaha, T.L., Chen, Y., Ravishankar, B., Van Rooijen, N., Karlsson, M.C. , 2011. Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen. Blood. vol. 117. pp. 5403-5412. (#607)



• Cook, P.C., Aynsley, S.A., Turner, J.D., Jenkins, G.R., Van Rooijen, N., Leeto, M., Brombacher, F., Mountford, A.P. , 2011. Multiple helminth infection of the skin causes lymphocyte hyporesponsiveness mediated by Th2 conditioning of dermal myeloid cells . PLoS Pathog.. vol. 7(3). pp. e1001323. (#606)



• Murphy, E.A., Davis, J.M., McClellan, J.L., Carmichael, M.D., Van Rooijen, N., Gangemi, J.D. , 2011. Susceptibility to infection and inflammatory response following influenza virus (H1N1, A/PR/8/34) challenge: Role of macrophages. J. Interferon Cytokine Res.. vol. 31. pp. 501-508. (#605)



• Hashimoto, D., Chow, A., Greter, M., Saenger, Y., Kwan, W-H., Leboeuf, M., Ginhoux, F., Ochando, J.C., Kunisaki, Y., Van Rooijen, N., Liu, C., Teshima, T., Heeger, P.S., Stanley, E.S., Frenette, P.S., Merad, M. , 2011. Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J. Exp. Med.. vol. 208. pp. 1069-1082. (#604)



• Soderquest, K., Powell, N., Luci, C., Van Rooijen, N., Hidalgo, A., Geissmann, F., Walzer, T., Lord, G.M., Martin-Fontecha, A. , 2011. Monocytes control natural killer cell differentiation to effector phenotypes. Blood. vol. 117. pp. 4511-4518. (#603)



• Potteau, S., Gautier, E.L., Hutchison, S.B., Van Rooijen, N., Rader, D.J., Thomas, M.J., Sorci-Thomas, M.G., Randolph, G.J. , 2011. Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of apoE-/- mice during disease regression. J. Clin. Invest. . vol. 121. pp. 2025-2036. (#602)



• Alexander, K.A., Chang, M.K., Maylin, E.R., Kohler, T., Muller, R., Wu, A.C., Van Rooijen, N., Sweet, M.J., Hume, D.A., Raggatt, L.J., Pettit, A.R., 2011. Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. J. Bone Miner. Res.. vol. 26.. pp. 1517-1532. (#601)



• Miyairi, I., Laxton, J.D., Wang, X., Obert, C.A., Venkat, R.R., Tatireddigari, A., Van Rooijen, N., Hatch, T.P., Byrne, G.I., 2011. Chlamydia psittaci genetic variants differ in virulence by modulation of host immunity. J. Infect. Dis.. vol. 204. pp. 654-663. (#600)



• Markovic, D.S., Vinnakota, K., Van Rooijen, N., Kiwit, J., Synowitz, M., Glass, R., Kettenmann, H. , 2011. Minocycline reduces glioma expansion and invasion by attenuating microglial MT1- MMP expression. Brain Behav. Immun.. vol. 25. pp. 624-628. (#599)



• Jonsson, F., Mancardi, D.A., Kita, Y., Karasuyama, H., Iannascoli, B., Van Rooijen, N., Shimizu, T., Daeron, M., Bruhns, P. , 2011. Mouse and human neutrophils induce anaphylaxis. J. Clin. Invest. . vol. 121. pp. 1484-1496. (#597)



• Bhatia, S., Fei, M., Yarlagadda, M., Qi, Z., Akira, S., Saijo, S., Iwakura, Y., Van Rooijen, N., Gibson, G.A., St Croix, C.M., Ray, A., Ray, P., 2011. Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype. PLoS One. vol. 6(1). pp. e15943. (#596)



• Mott, K.R., Gate, D., Zandian, M., Allen, S.J., Rajasagi, N.K., Van Rooijen, N., Chen, S., Arditi, M., Rouse, B.T., Flavell, R.A., Town, T., Ghiasi, H. , 2011. Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Invest. Ophth. Vis. Res. . vol. 52. pp. 2321-2333. (#595)



• Chow, A., Lucas, D., Hidalgo, A., Mendez-ferrer, S., Hashimoto, D., Scheiermann, C., Battista, M., Leboeuf, M., Prophete, C., Van Rooijen, N., Tanaka, M., Merad, M., Frenette, P.S. , 2011. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J. Exp. Med.. vol. 208. pp. 261-271. (#594)



• Acquati, F., Bertilaccio, S., Grimaldi, A., Monti, L., Cinquetti, R., Bonetti, P., Lualdi, M., Vidalino, L., Fabbri, M., Sacco, M.G., Van Rooijen, N., Campomenosi, P., Vigetti, D., Passi, A., Riva, C., Capella, C., Sanvito, F., Doglioni, C., Gribaldo, L., Macchi, P., Sica, A., Noonan, D.M., Ghia, P., Taramelli, R., 2011. Microenvironmental control of malignancy exerted by RNASET2. A widely conserved extracellular RNase. Proc. Natl. Acad. Sci. USA. vol. 108. pp. 757-761. (#593)



• Mancardi, D.A., Jonsson, F., Iannascoli, B., Khun, H., Van Rooijen, N., Huerre, M., Daeron, M., Bruhns, P., 2011. The murine high affinity IgG receptor FcgammaRIF is sufficient for autoantibody-induced arthritis. J. Immunol.. vol. 186. pp. 1899-1903. (#592)



• El Bakkouri, K., Descamps, F., De Filette, M., Smet, A., Festjens, E., Birkitt, A., Van Rooijen, N., Verbeek, S., Fiers, W., Saelens, X. , 2011. Universal vaccine based on ectodomain of matrix protein 2 of Influenza A: Fc receptors and alveolar macrophages mediate protection. J. Immunol.. vol. 186. pp. 1022-1031. (#591)



• Kurotaki, D., Kon, S., Bae, K., Ito, K., Matsui, Y., Nakayama, Y., Kanayama, M., Kimura, C., Narita, Y., Nishimura, T., Iwabuchi, K., Mack, M., Van Rooijen, N., Uede, T., Morimoto, J. , 2011. CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J. Immunol.. vol. 186. pp. 2229-2237. (#590)



• Johnson, E.E., Buhtoiarov, I.N., Baldeshwiler, M.J., Felder, M.A., Van Rooijen, N., Sondel, P.M., Rakhmilevich, A.L. , 2011. Enhanced T-cell-independent antitumor effect of cyclophosphamide combined with anti-CD40 mAb and CpG in mice. J. Immunotherapy. vol. 34. pp. 76-84. (#589)



• Song, J-M., Van Rooijen, N., Bozja, J., Compans, R., Kang, S-M. , 2011. Vaccination inducing broad and improved cross protection against multiple subtypes of influenza A viruses. Proc. Natl. Acad. Sci. USA. vol. 108. pp. 757-761. (#585)



• Song, J-M., Wang, B-Z., Park, K-M., Van Rooijen, N., Quan, F-S., Kim, M-C., Jin, H-T., Pekosz, A., Compans, R.W., Kang, S-M. , 2011. Influenza virus-like particles containing M2 induce broadly cross protective immunity. PLoS One. vol. 6(1); . pp. e14538. (#584)



• Ramos, P., Guy, E., Chen, N., Proenca, C.C., Gardenghi, S., Casu, C., Follenzi, A., Van Rooijen, N., Grady, R.W., de Sousa, M., Rivella, S. , 2011. Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis. Blood. vol. 117. pp. 1379-1389. (#582)



• Oshima, H., Hioki, K., Popivanova, B.K., Oguma, K., Van Rooijen, N., Ishikawa, T-O., Oshima, M., 2011. Prostaglandin E2 signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. Gastroenterology. vol. 140. pp. 596-607. (#581)



• Murray, L.A., Chen, Q., Kramer, M.S., Hesson, D.P., Argentieri, R.L., Peng, X., Gulati, M., Homer, R.J., Russell, T., Van Rooijen, N., Elias, J.A., Hogaboam, C.M., Herzog, E.L. , 2011. TGF-beta driven lung fibrosis is macrophage dependent and blocked by serum amyloid P. Int. J. Biochem. Cell Biol. . vol. 43. pp. 154-162. (#578)



• Kataoka, K., Nishiguchi, K.M., Kaneko, H., Van Rooijen, N., Kachi, S., Terasaki, H. , 2011. The roles of vitreal macrophages and circulating leukocytes in retinal neovascularization. Invest. Ophthalmol. Vis. Sci. . vol. 52. pp. 1431-1438. (#576)



• Kanematsu, Y., Kanematsu, M., Kurihara, C., Tada, Y., Tsou, T.L., Van Rooijen, N., Lawton, M.T., Young, W.L., Liang, E.I., Nuki, Y., Hashimoto, T. , 2011. Critical roles of macrophages in the formation of intracranial aneurysm. Stroke. vol. 42. pp. 173-178. (#575)



• Chao, J., Donham, P., Van Rooijen, N., Wood, J.G., Gonzalez, N.C. , 2011. Monocyte chemoattractant protein-1 released from alveolar macrophages mediates the systemic inflammation of acute alveolar hypoxia. Am. J. Respir. Cell Mol. Biol.. vol. 45. pp. 53-61. (#573)



• Chamberlain, C.S., Leiferman, E.M., Frisch, K.E., Wang, S., Yang, X., Van Rooijen, N., Baer, G.S., Brickson, S.L., Vanderby, R., 2011. The influence of macrophage depletion on ligament healing. Connective Tiss. Res.. vol. 52. pp. 203-211. (#568)



• Ianotti, C.A., Clark, M., Horn, K.P., Van Rooijen, N., Silver, J., Steinmetz, M.P. , 2011. A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI. Exp. Neurol.. vol. 230. pp. 3-15. (#548)



• Van Weering H.R.J., Boddeke, H.W.G.M., Vinet, J., Brouwer, N., De Haas, A.H., Van Rooijen, N., Thomsen, A.R., Biber, K.P.H. , 2011. CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus. Hippocampus. vol. 21. pp. 220-232. (#521)

2010:

• Lai, J-F., Zindl, C.L., Duffy, L.B., Atkinson, T.P., Jung, J.W., Van Rooijen, N., Waites, K.B., Krause, D.C., Chaplin, D.D. , 2010. Critical role of macrophages and their activation via MyD88-NFkappaB signaling in lung innate immunity to Mycoplasma pneumoniae. PLoS One. vol. 5(12). pp. e14417. (#587)



• Stienstra, R., Joosten, L.A., Koenen, T., Van Tits, B., Van Diepen, J.A., Van den Berg, S.A., Rensen, P.C., Voshol, P.J., Fantuzzi, G., Hijmans, A., Kersten, S., Muller, M., Van den Berg, W.B., Van Rooijen, N., Wabitsch, M., Kullberg, B.J., Van der Meer, J.W., Kanneganti, T., Tack, C.J., Netea, M.G. , 2010. The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab.. vol. 12. pp. 593-605. (#586)



• Archambaud, C., Salcedo, S.P., Lelouard, H., Devilard, E., de Bovis, B., Van Rooijen, N., Gorvel, J.P., Malissen, B. , 2010. Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. Eur. J. Immunol.. vol. 40. pp. 3458-3471. (#583)



• Feig, J.E., Pineda-Torra, I., Sanson, M., Bradley, M.N., Vengrenyuk, Y., Bogunovic, D., Gautier, E.L., Rubinstein, D., Hong, C., Liu, J., Wu, C., van Rooijen, N., Bhardwaj, N., Garabedian, M.J., Tontonoz, P., Fisher, E.A., 2010. LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. J. Clin. Invest. . vol. 120. pp. 4415-4424. (#580)



• Arwert, E.N., Lal, R., Quist, S., Rosewell, I., van Rooijen, N., Watt, F.M. , 2010. Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate. Proc. Natl. Acad. Sci. USA. vol. 107. pp. 19903-19908. (#579)



• Wunderlich, F.T., Strohle, P., Konner, A.C., Gruber, S., Tovar, S., Bronneke, H.S., Juntti-Berggren, L., Li, L.S., Van Rooijen, N., Libert, C., Berggren, P.O., Bruning, J.C. , 2010. Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Cell Metab.. vol. 12. pp. 237-249. (#574)



• Frimpong-Boateng, K., van Rooijen, N., Geiben-Lynn, R. , 2010. Regulatory T cells suppress natural killer cells during plasmid DNA vaccination in mice, blunting the CD8 T cell immune response by the cytokine TGFbeta. PLoS One. vol. 5(8). pp. e12281. (#572)



• Detalle, L., Su, D., Van Rooijen, N., Coutelier, J-P., 2010. Immunoglobulin M antiplatelet autoantibodies from mice immunized with rat platelets induce thrombocytopenia and platelet function impairment. Exp. Biol. Med.. vol. 235. pp. 1464-1471. (#571)



• Fabricio, K., Manix, c., Tian, H., Van Rooijen, N., Pirofski, L.A., 2010. The efficacy of pneumococcal capsular polysaccharide-specific antibodies to serotype 3 Streptococcus pneumoniae requires macrophages . Vaccine. vol. 28. pp. 7542-7550. (#570)



• Weisel, F.J., Appelt, U.K., Schneider, A.M., Horlitz, J.U., Van Rooijen, N., Korner, H., Mach, M., Winkler, T.H., 2010. Unique requirements for reactivation of virus-specific memory B lymphocytes. J. Immunol.. vol. 185. pp. 4011-4021. (#569)



• Mount, A.M., Masson, F., Kupresanin, F., Smith, C.M., May, J.S., Van Rooijen, N., Stevenson, P.G., Belz, G.T. , 2010. Interference with dendritic cell populations limits early antigen presentation in chronic {gamma}- Herpesvirus-68 infection. J. Immunol.. vol. 185. pp. 3669-3676. (#567)



• Bradshaw, A., Parker, A., Duffy, M., Coughlan, L., Van Rooijen, N., Kahari, V-M., Nicklin, S., Baker, A. , 2010. Requirements for receptor engagement during infection by Adenovirus complexed with blood coagulation factor X. PLoS Pathog.. vol. 6(10). pp. e1001142. (#565)



• Winkler, I.G., Sims, N.A., Pettit, A.R., Barbier, V., Nowlan, B., Helwani, F., Poulton, I.J., Van Rooijen, N., Alexander, K.A., Raggat, L.J., Levesque, J-P. , 2010. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood. vol. 116. pp. 4815-4828. (#564)



• Ly, L.V., Baghat, A., Versluis, M., Jordanova, E.S., Van Rooijen, N., Van Hall, T., Van der Velden, P.A., Jager, M.J. , 2010. In aged mice, outgrowth of intraocular melanoma depends on pro-angionic M2 type macrophages. J. Immunol.. vol. 185. pp. 3481-3488. (#563)



• Ishida, W., Fukuda, K., Kajisako, M., Takahashi, A., Sumi, T., Van Rooijen, N., Fukushima, A. , 2010. Conjunctival macrophages act as antigen-presenting cells in the conjunctiva during the development of experimental allergic conjunctivitis. Mol. Vision. vol. 16. pp. 1280-1285. (#562)



• Arnold, l., Kumar Tyagi, R., Mejia, P., Van Rooijen, N., Perignon, J.L., Druilhe, P. , 2010. Analysis of innate defences against Plasmodium falciparum in immunodeficient mice. Malar. J.. vol. 9. pp. 197. (#561)



• Steel, C.D., Kim, W.K., Sanford, L.D., Wellman, L.L., Burnett, S., Van Rooijen, N., Ciavarra, R.P. , 2010. Distinct macrophage subpopulations regulate viral encephalitis but not viral clearance in the CNS. J. Neuroimmunol.. vol. 226. pp. 81-92. (#560)



• Villaran, R.F., Espinosa-Oliva, A.M., Sarmiento, M., de Pablos, R.M., Arguelles, S., Delgado-Cortes, M.J., Sobrino, V., van Rooijen, N., Venero, J.L., Herrera, A.J., Cano. J., Machado, A., 2010. Ulcerative colitis exacerbates LPS-induced damage to the nigral dopaminergic system: Potential risk factor in Parkinson’s disease. J. Neurochem.. vol. 114. pp. 1687-1700. (#559)



• Hylton, D.J., Hoffman, S.M., Van Rooijen, N., Tomlinson, S., Fleming, S.D. , 2010. Macrophage produced IL-12p70 mediates hemorrhage-induced damage in a complement dependent manner. Shock. vol. 34. pp. 467-474. (#558)