Publications

2009:

• Roychowdhury, S., McMullen, M.R., Pritchard, M.T., Hise, A.G., Van Rooijen, N., Medof, M.E., Stavitsky, A.B., Nagy, L.E. , 2009. An early complement-dependent and TLR-4 independent phase in the pathogenesis of ethanol-induced liver injury. Hepatology. vol. 49. pp. 1326-1334. (#473)



• Oflazoglu, E., Stone, I.J., Brown, L., Gordon, K.A., Van Rooijen, N., Jonas, M., Law, C.L., Grewal, I.S., Gerber, H.P., 2009. Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40. Brit. J. Cancer. vol. 100. pp. 113-117. (#471)



• Kolaczkowska, E., Grzybec, W., Van Rooijen, N., Piccard, H., Plytycz, B., Arnold, B., Opdenakker, G. , 2009. Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis. J. Leuk. Biol.. vol. 85. pp. 374-381. (#470)



• O’Dea, K.P., Wilson, M.R., Dokpesi, J.O., Wakabayashi, K., Tatton, L., Van Rooijen, N., Takata, M. , 2009. Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs towards acute injury. J. Immunol.. vol. 182. pp. 1155-1166. (#469)



• Nuki, Y., Matsumoto, M.M., Tsang, E., Young, W.L., Van Rooijen, N., Kurihara, C., Hashimoto, T. , 2009. Roles of macrophages in flow-induced outward vascular remodeling. J. Cereb. Blood Flow Metab. . vol. 29. pp. 495-503. (#468)



• Parker, A.L., Waddington, S.N., Buckley, S.M., Custers, J., Havenga, M.J., Van Rooijen, N., Goudsmit, J., McVey, J.H., Nickin, S.A., Baker, A.H. , 2009. Effect of neutralising sera on factor X-mediated adenovirus serotype 5 gene transfer. J. Virol.. vol. 83. pp. 479-483. (#467)



• Traeger, T., Kessler, W., Hilpert, A., Mikulcak, M., Entleutner, M., Koerner, P., Westerholt, A., Cziupka, K., Van Rooijen, N., Heidecke, C.D., Maier, S. , 2009. Selective depletion of alveolar macrophages in polymicrobial sepsis increases lung injury, bacterial load and mortality but does not affect cytokine release. Respiration. vol. 77. pp. 203-213. (#464)



• Wildenberg, M.E., Welzen-Coppens, J.M.C., Van Helden-Meeuwsen, C.G., Bootsma, H., Vissink, A., Van Rooijen, N., Van de Merwe, J.P., Drexhage, H.A., Versnel, M.A. , 2009. Increased frequency of CD16+ monocytes and the presence of activated dendritic cells in salivary glands in primary Sjogren’s syndrome. Ann. Rheum. Dis.. vol. 68. pp. 420-426. (#435)

2008:

• Brechot, N., Gomez, E., Bignon, M., Khallou-Laschet, J., Dussiot, M., Cazes, A., Alanio-Brechot, C., Durand,M., Philippe, J., Silvestre, J-S., Van Rooijen, N., Corvol, P., Nicoletti, A., Chazaud, B., Germain, S. , 2008. Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice. PLoS One. vol. 3(12). pp. e 3950. (#472)



• Lee, P.Y., Kumagai, Y., Li, Y., Takeuchi, O., Yoshida, H., Weinstein, J., Kellner, E.S., Nacionales, D., Barker, T., Kelly-Scumpia, K., Van Rooijen, N., Kumar, H., Kawai, T., Satoh, M., Akira, S., Reeves, W.H. , 2008. TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus. J. Exp. Med.. vol. 205. pp. 2995-3006. (#466)



• Tang, P.C.Y., Qin, L., Zielonka, J., Zhou, J., Matte-Martone, C., Bergaya, S., Van Rooijen, N., Shlomchik, W.D., Min, W., Sessa, W.C., Pober, J.S., Tellides, G. , 2008. MyD88-dependent superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. J. Exp. Med.. vol. 205. pp. 3159-3171. (#465)



• Galea, I., Felton, L.M., Waters, S., Van Rooijen, N., Perry, V.H., Newman, T.A. , 2008. Immune-to- brain signalling: the role of cerebral CD163-positive macrophages. Neurosci. Lett. . vol. 448. pp. 41-46. (#463)



• Engel, D.R., Maurer, J., Tittel, A., Weisheit, C., Cavlar, T., Schumak, B., Limmer, A., Van Rooijen, N., Trautwein, C., Tacke, F., Kurts, C., 2008. CCR2 mediates homeostatic and inflammatory release of Gr1high monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection. J. Immunol.. vol. 181. pp. 5264-5271. (#462)



• Okamoto, A., Fujio, K., van Rooijen, N., Tsuno, N.H., Takahashi, K., Tsurui, H., Hirose, S., Elkon, K.B., Yamamoto, K. , 2008. Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice. J. Immunol.. vol. 181. pp. 5264-5271. (#461)



• Farber, K., Synowitz, M., Zahn, G., Vossmeyer, D., Stragies, R., Van Rooijen, N., Kettenmann, H. , 2008. An alpha 5 beta 1 integrin inhibitor attenuates glioma growth. Mol. Cell. Neurosci.. vol. 39. pp. 579-585. (#460)



• Corjon, S., Wortmann, A., Engler, T., Van Rooijen, N., Kochanek, S., Kreppel, F., 2008. Targeting of Adenovirus vectors to the LRP receptor family with the high-affinity ligand RAP via combined genetic and chemical modification of the pIX capsomere. Mol. Ther.. vol. 16. pp. 1813-1824. (#458)



• Horn, K,P., Busch, S, A., Hawthorne, A, L., Van Rooijen, N., Silver, J. , 2008. Another barrier to regeneration in the CNS: Activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. J. Neuroscience. vol. 28. pp. 9330-9341. (#457)



• Bystrom, J., Evans, I., Newson, J., Stables, M., Toor, I., Van Rooijen, N., Crawford, M., Colville-Nash, P., Farrow, S., Gilroy, D.W. , 2008. Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood. vol. 112. pp. 4117-4127. (#455)



• Geiben-Lynn, R., Greenland, J. R., Frimpong-Boateng, K., Van Rooijen, N., Hovav, A-H., Letvin, N. L., 2008. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses. Blood. vol. 112. pp. 4585-4590. (#454)



• Lois, N., Dawson, R., Townend, J., McKinnon, A.D., Smith, G.C., Van ‘t Hof, R., Van Rooijen, N., Forrester, J.V. , 2008. Effect of short-term macrophage depletion in the development of posterior capsule opacification in rodents . Brit. J. Ophthalmol.. vol. 92. pp. 1528-1533. (#453)



• Hippen, K.L., Harker-Murray, P., Porter, S.B., Merkel, S.C., Londer, A., Taylor, D.K., Bina, M., Panoskaltsis-Mortari, A., Rubinstein, P., Van Rooijen, N., Golovina, T.N., Suhoski, M.M., Miller, J.S., Wagner, J.E., June, C.H., Riley, J.L., Blazar, B.R. , 2008. Umbilical cord blood regulatory T cell (Treg) expansion and functional effects of tumor necrosis factor receptor (TNFR) family members OX40 and 4-1BB expressed on artificial antigen-presenting cells (aAPCs). Blood. vol. 112. pp. 2847-2857. (#452)



• Ganesh Sivanandam, V., Stephen, S.L., Hernandez—Alcoceba, R., Alzuguren, P., Zabala, M., Van Rooijen, N., Qian, C., Berger, I., Gross, M-L, Prieto, J., Kochanek, S. , 2008. Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1. J. Gene Med.. vol. 10. pp. 1083-1091. (#451)



• Huang, Y., Li, Z., Wang, N., Van Rooijen, N., Cui, Q. , 2008. Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds. BMC Neuroscience. vol. 9. pp. 78. (#450)



• Appledorn, D.M., Patial, S., McBride, A., Godbehere, S., Van Rooijen, N., Parameswaran, N., Amalfitano, A. , 2008. Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J. Immunol.. vol. 181. pp. 2134-2144. (#449)



• Qiu, H., Fan, Y., Joyee, A.G., Wang, S., Han, X., Bai, H., Jiao, L., Van Rooijen, N., Yang, X., 2008. Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J. Immunol.. vol. 181. pp. 2092-2102. (#448)



• Zhou, Z., Barrett, R.P., McClellan, S.A., Zhang, Y., Szliter, E.A., Van Rooijen, N., Hazlett, L.D. , 2008. Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection. Invest. Ophthalmol. Vis. Sci.. vol. 49. pp. 4458-4467. (#447)



• Getts, D.R., Terry, R.L., Teague Getts, M., Muller, M., Rana, S., Shrestha, B., Radford, J., Van Rooijen, N., Campbell, I.L., King, N.J.C. , 2008. Ly6c+ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. J. Exp. Med.. vol. 205. pp. 2319-2337. (#446)



• Fux, M., Van Rooijen, N., Owens, T. , 2008. Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation. J. Neuroimmunol.. vol. 203. pp. 64-72. (#445)



• Campion, S.N., Johnson, R., Aleksunes, L.M., Goedken, M.J., Van Rooijen, N., Scheffer, G.L., Cherrington, N.J., Manautou, J.E. , 2008. Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function. Am. J. Physiol.. vol. 295. pp. G294-G304. (#444)



• Horne, P.H., Zimmerer, J.M., Fisher, M., Lunsford, K.E., Nadasdy, G., Nadasdy, T., Van Rooijen, N., Bumgardner, G.L. , 2008. Critical role of effector macrophages in mediating CD4-dependent alloimmune injury of transplanted liver parenchymal cells. J. Immunol.. vol. 181. pp. 1224-1231. (#443)



• Campbell, S.J., Zahid, I., Losey, P., Law, S., Bilgen, M., Van Rooijen, N., Davis, A.E.M., Anthony, D.C. , 2008. Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord. Neuropharmacol.. vol. 55. pp. 780-787. (#441)



• Theurl, M., Theurl, I., Hochegger, K., Obrist, P., Subramaniam, N., Van Rooijen, N., Schuemann, K., Weiss, G. , 2008. Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression. J. Mol. Med.. vol. 86. pp. 825-835. (#440)



• Bem, R.A., Farnand, A.W., Wong, V., Koski, A., Rosenfeld, M.E., Van Rooijen, N., Frevert, C.W., Martin, T.R., Matute-Bello, G. , 2008. Depletion of resident alveolar macrophages does not prevent FAS-mediated lung injury in mice. Am. J. Physiol.. vol. 295. pp. L314-L325. (#439)



• Van Rooijen N. , 2008. Liposomes for targeting of antigens and drugs: Immunoadjuvant activity and liposome-mediated depletion of macrophages. J. Drug Targeting. vol. 16. pp. 529-534. (#438)



• McGill, J., Van Rooijen, N., Legge, K.L. , 2008. Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J. Exp. Med.. vol. 205. pp. 1635-1646. (#437)



• Roth, K.M., Oghumu, S., Satoskar, A.A., Gunn, J.S., Van Rooijen, N., Satoskar, A.R. , 2008. Respiratory infection with Francisella novicida induces rapid dystrophie cardiac calcinosis (DCC). FEMS Immunol. Med. Microbiol. . vol. 53. pp. 72-78. (#436)



• Zhao, A., Urban Jr, J.F., Anthony, R.M., Sun, R., Stiltz, J., Van Rooijen, N., Wynn, T.A., Gause, W.C., Shea-Donohue, T. , 2008. Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology. vol. 135. pp. 217-225. (#434)



• Miselis, N.R., Wu, Z.J., Van Rooijen, N., Kane, A.B. , 2008. Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Mol. Cancer Ther.. vol. 7. pp. 788-799. (#433)



• Murphy, E.A., Davis, J.M., Brown, A.S., Carmichael, M.D., Carson, J.A., Van Rooijen, N., Chaffar, A., Mayer, E.P. , 2008. Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. Am. J. Physiol.. vol. 294. pp. R1593-R1599. (#432)



• Robertson, C.M., Perrone, E.E., McConnell, K.W., Dunne, W.M., Boody, B., Brahmbhatt, T., Diacovo, M.J., Van Rooijen, N., Hogue, L.A., Cannon, C.L., Buchman, T.G., Hotchkiss, R.S., Coopersmith, C.M. , 2008. Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. J. Surg. Res.. vol. 150. pp. 278-285. (#431)



• Lee, P.Y., Weinstein, J.S., Nacionales, D.C., Scumpia, P.O., Li, Y., Butfiloski, E.J., Van Rooijen, N., Moldawer, L.L., Satoh, M., Reeves, W.H. , 2008. A novel type1 IFN–producing cell subset in murine lupus. J. Immunol.. vol. 180. pp. 5101-5108. (#430)



• Kaparakis, M., Walduck, A.K., Price, J.D., Pedersen, J.S., Van Rooijen, N., Pearse, M.J., Wijburg, O.L.C., Strugnell, R.A. , 2008. Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice. Infect. Immun.. vol. 76. pp. 2235-2239. (#429)



• Soehnlein, O., Oehmcke, S., Ma, X., Rothfuchs, A.G., Frithiof, R., Van Rooijen, N., Morgelin, M., Herwald, H., Lindbom, L. , 2008. Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein. Eur. Respir. J.. vol. 32. pp. 405-412. (#428)



• Bakker, E.N.T.P., Matlung, H.L., Bonta, P., De Vries, C.J., Van Rooijen, N., Van Bavel, E. , 2008. Blood flow-dependent arterial remodeling is facilitated by inflammation but directed by vasculat tone. Cardiovasc. Res.. vol. 78. pp. 341-348. (#427)



• Kim, H.M., Lee, Y.W., Lee, K.J., Kim, H.S., Cho, S.W., Van Rooijen, N., Guan, Y., Seo, S.H. , 2008. Alveolar macrophages are indispensable for controlling influenza viruses in lungs of pigs. J. Virol.. vol. 82. pp. 4265-4274. (#426)



• Koh, A.Y., Kohler, J.R., Coggshall, K.T., Van Rooijen, N., Pier, G.B. , 2008. Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog.. vol. 4(2). pp. e35. (#425)



• Huang, Y., Cen, L-P., Luo, J-M., Wang, N., Zhang, M-Z., van Rooijen, N., Pang, C.P., Cui, Q. , 2008. Differential roles of phosphatidylinositol 3-kinase/akt pathway in retinal ganglion cell survival in rats with or without acute ocular hypertension. Neuroscience. vol. 153. pp. 214-225. (#424)



• Moraes, L.B., Murakami, A.H., Fontes, B., Poggetti, R.S., Van Rooijen, N., Younes, R.N., Heimbecker, A.M., Birolini, D. , 2008. Gut ischemia/reperfusion induced acute lung injury is an alveolar macrophage dependent event. J. Trauma. vol. 64. pp. 1196-1201. (#423)



• Waddington, S.N., McVey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, H., Pink, R., Buckley, S.M.K., Greig, J.A., Denby, L., Custers, J., Morita, T., Francischetti, I.M.B., Monteiro, R.Q., Barouch, D.H., Van Rooijen, N., Napoli, C., Havenga, M.J.E., Nicklin, S.A., Baker, A.H. , 2008. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell. vol. 132. pp. 397-409. (#422)



• Jakubzick, C., Tacke, F., Ginhoux, F., Wagers, A.J., Van Rooijen, N., Mack, M., Merad, M. Randolph, G.J. , 2008. Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J. Immunol.. vol. 180. pp. 3019-3027. (#421)



• Fracarollo, D., Galuppo, P., Schraut, S., Kneitz, S., Van Rooijen, N., Ertl, G., Bauersachs, J. , 2008. Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response. Hypertension. vol. 51. pp. 905-914. (#420)



• Rival, C., Theas, M.S., Suescun, M.O., Jacobo, P., Guazzone, V., Van Rooijen, N., Lustig, L. , 2008. Functional and phenotypical characteristics of testicular macrophages in experimental autoimmune orchitis. J. Pathol.. vol. 215. pp. 108-117. (#419)



• Bryer, S.C., Fantuzzi, G., Van Rooijen, N., Koh, T.J. , 2008. Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis annd skeletal muscle regeneration. J. Immunol.. vol. 180. pp. 1179-1188. (#418)



• Wakim, L., Waithman, J., Van Rooijen, N., Heath, W.R., Carbone, F.R. , 2008. Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science. vol. 319. pp. 198-202. (#416)



• Pistea, A., Bakker, E.N., Spaan, J.A., Hardeman, M.R., Van Rooijen, N., Vanbavel, E. , 2008. Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: Role of transglutaminases. J. Vasc. Res. . vol. 45. pp. 10-18. (#411)



• Lidbury, B.A., Suhrbier, A., Tarkowski, A., Van Rooijen, N., Mahalingam, S. , 2008. Macrophage-derived proinflammatory factors contribute to the development of arthritis and myositis after infection with an arthrogenic alphavirus. J. Infect. Dis. vol. 197. pp. 1585-1593. (#403)



• Kelly, M.M., McNagny, K., Williams, D.L., Van Rooijen, N., Maxwell, L., Gwozd, C., Mody, C.H., Kubes, P. , 2008. The lung responds to zymosan in a unique manner independent of Toll-like receptors, complement and dectin-1. Am. J. Respir. Cell Mol. Biol.. vol. 38. pp. 227-238. (#398)

2007:

• Mott, K., Brick, D.J., Van Rooijen, N., Ghiasi, H., 2007. Macrophages are important determinants of acute ocular HSV-1 infection in immunized mice. Invest. Ophthalmol. Vis. Res.. vol. 48. pp. 5605-5615. (#417)



• Fischer, C., Jonckx, B., Mazzone, M., Zacchigna, S., Loges, S., Pattarini, L., Chorianopoulos, E., Liesenborghs, L., Koch, M., De Mol, M., Autiero, M., Wyns, S., Plaisance, S., Moons, L., Van Rooijen, N., Giacca, M., Stassen, J-M., Dewerchin, M., Collen, D., Carmeliet, P, 2007. Anti-PIGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell. vol. 131. pp. 463-475. (#414)



• Couper, K.N., Blount, D.G., Hafalla, J.C., Van Rooijen, N., De Souza, J.B., Riley, E.M. , 2007. Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitaemia. Infect. Immun.. vol. 75. pp. 5806-5818. (#413)



• Oflazoglu,, E., Stone, I.J., Gordon, G.A., Grewal, I.S., Van Rooijen, N., Law, C-L., Gerber, H-P. , 2007. Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30. Blood. vol. 110. pp. 4370-4372. (#412)



• Flierl, M.A., Rittirsch, D., Nadeau, B.A., Chen, A.J., Sarma, J.V., Zetoune, F.S., McGuire, S.R., List, R.P., Day, D.E., Hoesel, L.M., Gao, H., Van Rooijen, N., Huber-Lang, M.S., Neubig, R.R., Ward, P.A. , 2007. Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature. vol. 449. pp. 721-725. (#410)



• Ohnmacht, C., Pullner, A., Van Rooijen, N., Voehringer, D., 2007. Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity. J. Immunol.. vol. 179. pp. 4766-4774. (#409)



• Junt, T., Moseman, E.A., Iannacone, M., Massberg, S., Lang, P.A., Boes, M., Fink, K., Henrickson, S.E., Shayakhmetov, D.M., Van Rooijen, N., Mempel, T., Whelan, S.P., Von Adrian, U.H. , 2007. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. vol. 450. pp. 110-114. (#408)



• Borders, A.S., Hersh, M.A., Getchell, M.L., Van Rooijen, N., Cohen, D.A., Stromberg, A.J., Getchell, T.V. , 2007. Macrophage-mediated neuroprotection and neurogenesis in the olfactory epithelium. Physiol. Genomics. vol. 31. pp. 531-543. (#407)



• Price, J.D., Simpfendorfer, K.R., Mantena, R.R., Holden, J., Heath, W.R., Van Rooijen, N., Strugnell, R.A., Wijburg, O.L.C. , 2007. Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium. Infect. Immun.. vol. 75. pp. 5753-5762. (#406)



• Kolaczkowska, E., Lelito, M., Kozakiewicz, E., Van Rooijen, N., Plytycz, B., Arnold, B. , 2007. Resident peritoneal leukocytes are important sources of MMP-9 during zymosan peritonitis: Superior contribution of macrophages over mast cells. Immunol. Lett.. vol. 113. pp. 99-106. (#405)



• Khandelwal, S., Van Rooijen, N., Saxena, R.K. , 2007. Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation. Transfusion. vol. 47. pp. 1725-1732. (#404)



• Huang, Y., Cen, L-P., Choy, K.W., van Rooijen, N., Wang, N., Pang, C.P., Cui, Q. , 2007. JAK/STAT pathway mediates retinal ganglion cell survival after acute ocular hypertension but not under normal condition. Exp. Eye Res.. vol. 85. pp. 684-695. (#402)



• Huang, Y., Li, Z., Van Rooijen, N., Wang, N., Pang, C.P., Cui, Q. , 2007. Different responses of macrophages in retinal ganglion cell survival after acute ocular hypertension in rats with different autoimmune backgrounds. Exp. Eye Res.. vol. 85. pp. 659-666. (#401)



• Galea, I., Bernardes-Silva, M., Forse, P.A., Van Rooijen, N., Liblau, R.S., Perry, V.H. , 2007. An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J. Exp. Med.. vol. 204. pp. 2023-2030. (#400)



• Dipasquale, D.M., Cheng, M., Billich, W., Huang, S.A., Van Rooijen, N., Hornberger, T., Koh, T.J. , 2007. Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice. Am. J. Physiol. Cell Physiol. . vol. 293. pp. C1278-1285. (#399)



• Wang, H., Madariaga, M.L., Wang, S., Van Rooijen, N., Oldenborg, P-A., Yang, Y-G. , 2007. Lack of CD47 on non-hematopoietic cells induces split macrophage tolerance to CD47null cells. Proc. Natl. Acad. Sci. U S A. vol. 104. pp. 13744-13749. (#397)



• Gonzalez, N.C., Allen, J., Blanco, V.G., Schmidt, E.J., Van Rooijen, N., Wood, J.G. , 2007. Alveolar macrophages are necessary for the systemic inflammation of alveolar hypoxia. J. Appl. Physiol.. vol. 103. pp. 1386-1394. (#396)



• Kumar, K.A., Garcia, C.R.S., Chandran, V.R., Van Rooijen, N., Zhou, Y., Winzeler, E., Nussenzweig, V. , 2007. Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell pasage activity. Molec. Biochem. Parasitol.. vol. 156. pp. 32-40. (#395)



• Fulci, G., Dmitrieva, N., Gianni, D., Fontana, E.J., Pan, X., Lu, Y., Kaufman, C,S., Kaur, B., Lawler, S.E., Lee, R.J., Marsh, C.B., Brat, D.J., Van Rooijen, N., Rachamimov, A.S., Hochberg, F.H., Weissleder, R., Martuza, R.L., Chiocca, E.A., 2007. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res.. vol. 67. pp. 9398-9406. (#394)



• Greten, F.R., Arkan, M.C., Bollrath, J., Hsu, L-C., Goode, J., Miething, C., Göktuna, S.I., Neuenhahn, M., Fierer, J., Paxian, S., Van Rooijen, N., Xu, Y., O’Cain, T., Jaffee, B.B., Busch, D.H., Duyster, J., Schmid, R.M., Eckmann, L., Karin, M. , 2007. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell. vol. 130. pp. 918-931. (#393)



• Luo, J.M., Cen, L.P., Zhang, X-M., Chiang, S.W.Y., Huang, Y., Lin, D., Fan, Y.M., Van Rooijen, N., Lam, D.S.C., Pang, C.P., Cui, Q. , 2007. P13K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury. Eur. J. Neurosci.. vol. 26. pp. 828-842. (#392)



• Bauer, D., Wasmuth, S., Hermans, P., Hennig, M., Meller, K., Meller, D., Van Rooijen, N., Tseng, S.C.G., Steuhl, K-P., Heiligenhaus, A. , 2007. On the influence of neutrophils in corneas with necrotizing HSV-1 keratitis following amniotic membrane transplantation. Exp. Eye Res.. vol. 85. pp. 335-345. (#391)



• Rivera, C.A., Adegboyega, P., Van Rooijen, N., Tagalicud, A., Allman, M., Wallace, M., 2007. Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J. Hepatol.. vol. 47. pp. 571-579. (#390)



• Reese, T.A., Liang, H-E., Tager, A.M., Luster, A.D., Van Rooijen, N., Voehringer, D., Locksley, R.M. , 2007. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. vol. 447. pp. 92-96. (#389)



• Cen, L-P., Luo, J-M., Zhang, C-W., Fan, Y-M., Song, Y., So, K-F., Van Rooijen, N., Pang, C-P., Lam, D.S.C., Cui, Q. , 2007. Chemotactic effect of ciliary neurotrophic factor on macrophages in retinal ganglion cell survival and axonal regeneration. Invest. Ophthalmol. Vis. Res.. vol. 48. pp. 4257-4266. (#387)



• Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., Van Rooijen, N., Plonquet, A., Gherardi, R.K., Chazaud, B. , 2007. Inflammatory monocytes recruited after sceletal muscle injury switch into anti-inflammatory macrophages to support myogenesis. J. Exp. Med.. vol. 204. pp. 1057-1069. (#386)



• Robinson-Smith, T.M., Isaacsohn, I., Mercer, C.A., Zhou, M., Van Rooijen, N., Husseinzadeh, N., McFarland-Mancini, M., Drew, A.F. , 2007. Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer Res.. vol. 67. pp. 5708-5716. (#385)



• Van Amerongen, M.J., Harmsen, M.C., Van Rooijen, N., Petersen, A.H., Van Luyn, M.J. , 2007. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am. J. Pathol.. vol. 170. pp. 818-829. (#384)



• Gazzaniga, S., Bravo, A., Guglielmotti, A., Van Rooijen, N., Maschi, F., Vecchi, A., Mantovani, A., Mordoh, J., Wainstok, R. , 2007. Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J. Invest. Dermatol.. vol. 127. pp. 2031-2041. (#383)



• Smith, P., Mangan, N.E., Walsh, C.M., Fallon, R.E., McKenzie, A.N.J., Van Rooijen, N., Fallon, P.G. , 2007. Infection with a Helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J. Immunol.. vol. 178. pp. 4557-4566. (#382)



• Voehringer, D., Van Rooijen, N., Locksley, R.M. , 2007. Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages. J. Leuk. Biol.. vol. 81. pp. 1434-1444. (#381)



• Carbonetti, N.H., Artamonova, G.V., Van Rooijen, N., Ayala, V.I. , 2007. Pertussis toxin targets airway macrophages to promote Bordetella pertussis infection of the respiratory tract. Infect. Immun.. vol. 75. pp. 1713-1720. (#380)



• Mocanu, J.D., Yip, K.W., Li, J-H., Lunt, S.J., Moriyama, E.H., Wilson, B.C., Lo, K.W., Van Rooijen, N., Milosevic, M., Bastianutto, C., Liu, F-F. , 2007. Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy. Mol. Ther.. vol. 15. pp. 921-929. (#379)



• Lundberg, P., Welander, P.V., Edwards, C.K. 3rd, van Rooijen, N., Cantin, E. , 2007. Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2. J. Virol.. vol. 81. pp. 1451-1460. (#378)



• Tacke, F., Llodra, J., Kaplan, T.J., Jakubzick, C., Liu, J., Van Rooijen, N., Randolph, G.J. , 2007. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J. Clin. Invest. . vol. 117. pp. 185-194. (#377)



• Gray, M., Popovich, P.G., Van Rooijen, N., Gupta, R. , 2007. Macrophage depletion alters the blood nerve barrier without affecting Schwann cell function after neural injury. J. Neurosci. Res.. vol. 85. pp. 766-777. (#376)



• Borders, A.S., Getchell, M.L., Etscheidt, J.T., Van Rooijen, N., Cohen, D.A., Getchell, T.V. , 2007. Macrophage depletion in the murine olfactory epithelium leads to increased neuronal death and decreased neurogenesis. J. Compar. Neur.. vol. 501. pp. 206-218. (#375)



• Blom, A.B., Van Lent, P.L., Libregts, S., Holthuysen, A.E., Van der Kraan, P.M., Van Rooijen, N., Van den Berg, W.B. , 2007. Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: Involvement of matrix metalloproteinase 3. Arthritis Rheum.. vol. 56. pp. 147-157. (#372)



• McEarchern, J.A., Oflazoglu, E., Francisco, L., McDonagh, C.F., Gordon, K.A., Stone, I., Klussman, K., Turcott, E., Van Rooijen, N., Carter, P., Grewal, I.S., Wahl, A.F., Leung Law, C. , 2007. Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities. Blood. vol. 109. pp. 1185-1192. (#371)



• Baer, K., Roosevelt, M., Clarkson Jr., A.B., Van Rooijen, N., Schnieder, T., Frevert, U. , 2007. Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liver. Cell. Microbiol. vol. 9. pp. 397-412. (#368)

2006:

• Furtado, G.C., Pina, B., Tacke, F., Gaupp, S., Van Rooijen, N., Moran, T.M., Randolph, G.J., Ransohoff, R.M., Chensue, S.W., Raine, C.S., Lira, S.A. , 2006. A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells. J. Immunol.. vol. 177. pp. 6871-6879. (#374)



• Van Rooijen, N., Van Kesteren-Hendrikx, E. , 2006. The liposome mediated Macrophage Suicide Technique: A tool to study and manipulate macrophage activities.. In: “Liposome Technology” third edition, . vol. III, Gregory Gregoriadis ed. Informa Healthcare, USA.. pp. 303-316, (Chapter 16). (#373)



• Breitbach, K., Klocke, S., Tschernig, T., Van Rooijen, N., Baumann, U., Steinmetz, I. , 2006. Role of inducible nitric oxide synthase and NADPH oxidase in the early control of Burkholderia pseudomallei infection in mice. Infect. Immun.. vol. 74. pp. 6300-6309. (#370)