Publications

2006:

• Crettaz, J., Berraondo, P., Mauleon, I., Ochoa, L., Shankar, V., Barajas, M., Van Rooijen, N., Kochanek, S., Qian, C., Prieto, J., Hernandez-Alcoceba, R., Gonzales-Asequinolaza, G. , 2006. Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice. Hepatology. vol. 44. pp. 623-632. (#369)



• Anthony, R.M., Urban Jr, J.F., Alem, F., Hamed, H.A., Rozo, C.T., Boucher, J-L., Van Rooijen, N., Gause, W.C. , 2006. Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nature Medicine. vol. 12. pp. 955-960. (#367)



• Wang, H., Peters, T., Kess, D., Sindrilaru, A., Oreshkova, T., Van Rooijen, N., Stratis, A., Renkl, A.C., Sunderkötter, C., Wlaschek, M., Haase, I., Scharffetter-Kochanek, K. 2006. , 2006. Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J. Clin. Invest. . vol. 116. pp. 2105-2114. (#366)



• Stratis, A., Pasparakis, M., Rupec, R.A., Markur, D., Hartmann, K., Scharffetter-Kochanek, K., Peters, T., Van Rooijen, N., Krieg, T., Haase, I. , 2006. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J. Clin. Invest. . vol. 116. pp. 2094-2104. (#365)



• Keijser, S., De Keizer, R.J.W., Prins, F.A., Tanke, H.J., Van Rooijen, N., Vrensen, G.F.J.M., Jager, M.J. , 2006. A new model for limbal transplantation using E-GFP for follow-up of transplant survival. Exp. Eye Res.. vol. 83. pp. 1188-1195. (#364)



• Louten, J., Van Rooijen, N., Biron, C.A. , 2006. Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. J. Immunol.. vol. 177. pp. 3266-3272.. (#363)



• Synowitz, M., Glass, R., Faerber, K., Markovic, D., Kronenberg, G., Herrmann, K., Schnermann, J., Nolte, C., Van Rooijen, N., Kiwit, J., Kettenmann, H. , 2006. A1 adenosine receptors in microglia control glioblastoma - host interaction. Cancer Res.. vol. 66. pp. 8550-8557. (#362)



• Bakker, E.N.T.P., Pistea, A., Spaan, J.A.E., Rolf, T., De Vries, C.J., Van Rooijen, N., Candi, E., Van Bavel, E. , 2006. Arteries in mice defiecient for tissue-type transglutaminase: Possible compensation by macrophage-derived factor XIII. Circul. Res.. vol. 99. pp. 86-92. (#361)



• Qualls, J.E., Kaplan, A.M., Van Rooijen, N., Cohen, D.A. , 2006. Suppression of experimental colitis by intestinal mononuclear phagocytes. J. Leuk. Biol.. vol. 80. pp. 802-815. (#360)



• Kolaczkowska, E., Scislowska-Czarnecka, A., Chadzinska, M., Plytycz, B., Van Rooijen, N., Opdenakker, G., Arnold, B. , 2006. Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin. J. Leuk. Biol.. vol. 80. pp. 125-132. (#359)



• Agrawal, S., Anderson, P., Durbeej, M., Van Rooijen, N., Ivars, F., Opdenakker, G., Sorokin, L.M., 2006. Selective dystroglycan cleavage by macrophage gelatinases is essential for leukocyte extravasation in experimental autoimmune encephalomyelitis. J. Exp. Med.. vol. 203. pp. 1007-1019. (#358)



• Gehring, S., Dickson, E.M., San Martin, M.E., Van Rooijen, N., Papa, E.F., Harty, M.W., Tracy Jr, T.F., Gregory, S.H. , 2006. Kupffer cells abrogate cholestatic liver injury in mice. Gastroenterology. vol. 130. pp. 810-822. (#357)



• Morosan, S., Hez-Deroubaix, S., Lunel, F., Renia, L., Giannini, C., Van Rooijen, N., Battaglia, S., Blanc, C., Eling, W., Sauerwein, R., Hannoun, L., Belghiti, J., Brechot, C., Kremsdorf, D., Druilhe, P. , 2006. Liver-stage development of Plasmodium falciparum in a humanized mouse model. J. Infect. Dis.. vol. 193. pp. 996-1004. (#356)



• Boonman, Z.F.H.M., Schurmans, L.R.H.M., Van Rooijen, N., Melief, C.J.M., Toes, R.E.M., Jager, M.J. , 2006. Macrophages are vital in spontaneous intraocular tumor eradication. Invest. Ophthalmol. Vis. Res.. vol. 47. pp. 2959-2965. (#355)



• Golay, J., Cittera, E., Di Gaetano, N., Manganini, M., Mosca, M., Nebuloni, M., Van Rooijen, N., Vago, L., Introna, M. , 2006. The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes. Haematologica. Haematologica. vol. 91. pp. 176-183. (#354)



• Jakubzick, C., Tacke, F., Llodra, J., Van Rooijen, N., Randolph, G.J. , 2006. Modulation of dendritic cell trafficking to and from the airways. J. Immunol.. vol. 176. pp. 3578-3584. (#352)



• Tacke, F., Ginhoux, F., Jakubzick, C., Van Rooijen, N., Merad, M., Randolph, G.J. , 2006. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J. Exp. Med.. vol. 203. pp. 583-597. (#351)



• Le Borgne, M., Etchart, N., Goubier, A., Lira, S.A., Sirard, J.C., Van Rooijen, N., Caux, C., Ait-Yahia, S., Vicari, A., Kaiserlian, D., Dubois, B., 2006. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity. vol. 24. pp. 191-201. (#350)



• Summan, M., Warren, G.L., Mercer, R., Chapman, R., Hulderman, T., Van Rooijen, N., Simeonova, P.P., 2006. Macrophages and skeletal muscle regeneration: A clodronate-containing liposome depletion study. Am. J. Physiol.. vol. 290. pp. R1488-R1495. (#349)



• Stevenson, M., Boos, E., Herbert, C., Hale, A., Green, N., Lyons, M., Chandler, L., Ulbrich, K., Van Rooijen, N., Mautner, V., Fisher, K., Seymour, L. , 2006. Chick embryo lethal orphan virus can be polymer-coated and retargeted to infect mammalian cells. Gene Therapy. vol. 13. pp. 356-368. (#348)



• Mangan, N.E., Van Rooijen, N., McKenzie, A.N.J., Fallon, P.G., 2006. Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness. J. Immunol.. vol. 176. pp. 138-147. (#347)



• Moreno, A., Ferrer, E., Arahuetes, S., Eguiluz, C., Van Rooijen, N., Benito, A. , 2006. The course of infections and pathology in immunomodulated NOD/LtSz-SCID mice inoculated with Plasmodium falciparum laboratory lines and clinical isolates. Int. J. Parasitol.. vol. 36. pp. 361-369. (#345)



• Frid, M.G., Brunetti, J.A., Burke, D.L., Carpenter, T.C., Davie, N.J., Reeves, J.T., Roedersheimer, M.T., Van Rooijen, N., Stenmark, K.R. , 2006. Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am. J. Pathol.. vol. 168. pp. 659-669. (#344)



• Cote, C.K., Van Rooijen, N., Welkos, S.L., 2006. Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect. Immun.. vol. 74. pp. 469-480. (#343)



• Evans, K.J., Hansen, D.S., Van Rooijen, N., Buckingham, L.A., Schofield, L., 2006. Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes. Blood. vol. 107. pp. 1192-1199. (#342)



• Haque, A., Easton, A., Smith, D., O’Garra, A., Van Rooijen, N., Lertmemongkolchai, G., Titball, R.W., Bancroft, G.J., 2006. Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J. Infect. Dis. vol. 193. pp. 370-379. (#335)

2005:

• Keller, M., Gerbes, A.L., Kulhanek-Heinze, S., Gerwig, T., Grutzner, U., Van Rooijen, N., Vollmar, A.M., Kiemer, A.K. , 2005. Hepatocyte cytoskeleton during ischemia and reperfusion - influence of ANP-mediated p38 MAPK activation. World J. Gastroenterol.. vol. 11. pp. 7418-7429. (#353)



• Lawlor, K.E., Wong, P.K.K., Campbell, I.K., Van Rooijen, N., Wicks, I.P. , 2005. Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor. Arthritis Rheum.. vol. 52. pp. 3749-3754. (#346)



• Tumpey, T.M., Garcia-Sastre, A., Taubenberger, J.K., Palese, P., Swayne, D.E., Pantin-Jackwood, M.J., Schultz-Cherry, S., Solorzano, A., Van Rooijen, N., Katz, J.M., Basler, C.F., 2005. Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice. J. Virol.. vol. 79. pp. 14933-14944. (#341)



• Holtje, M., Hoffmann, A., Hofmann, F., Mucke, C., Grosse, G., Van Rooijen, N., Kettenmann, H., Just, I., Ahnert-Hilger, G., 2005. Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. J. Neurochem.. vol. 95. pp. 1237-1248. (#340)



• Ciavarra, R.P., Taylor, L., Greene, A.R., Yousefieh, N., Horeth, D., Van Rooijen, N., Steel, C., Gregory, B., Birkenbach, M., Sekellick, M. , 2005. Impact of macrophage and dendritic cell subset elimination on antiviral immunity, viral clearance and production of type 1 interferon. Virology. vol. 342. pp. 177-189. (#338)



• Markovic, D.S., Glass, R., Synowitz, M., Van Rooijen, N., Kettenmann, H., 2005. Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J. Neuropathol. Exp. Neurol.. vol. 64. pp. 754-762. (#337)



• Maruyama, K., Li, M., Cursiefen, C., Jackson, D.G., Keino, H., Tomita, M., Van Rooijen, N., Takenaka, H., D’Amore, P.A., Stein-Streilein, J., Losordo, D.W., Streilein, J.W., 2005. Inflammation-induced lymphangiogenesis in the corona arises from CD11b-positive macrophages. J. Clin. Invest. . vol. 115. pp. 2363-2372. (#336)



• Ali, S., King, G.D., Curtin, J.F., Candolfi, M., Xiong, W., Liu, C., Puntel, M., Cheng, Q., Prieto, J., Ribas, A., Kupiec-Weglinski, J., Van Rooijen, N., Lassmann, H., Lowenstein, P.R., Castro, M.G. , 2005. Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Res.. vol. 65. pp. 7194-7204. (#334)



• Oosterling, S.J., Van Der Bij, G.J., Meijer, G.A., Tuk, C. W., Van Garderen, E., Van Rooijen, N., Meijer, S., Van Der Sijp, J.R.M., Beelen, R.H.J., Van Egmond, M., 2005. Macrophages direct tumour histology and clinical outcome in a colon cancer model. J. Pathol.. vol. 207. pp. 147-155. (#333)



• Kresse, M., Latta, M., Kunstle, G., Riehle, H-M., Van Rooijen, N., Hentze, H., Tiegs, G., Biburger, M., Lucas, R., Wendel, A. , 2005. Kupffer cell expresses membrane-bound TNF and mediates Melphalan hepatoxicity via activation of both TNF receptors. J. Immunol.. vol. 175. pp. 4076-4083. (#332)



• Shao, X., Mednick, A., Alvarez, M., Van Rooijen, N., Casadevall, A., Goldman, D.L. , 2005. An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia. J. Immunol.. vol. 175 . pp. 3244-3251. (#331)



• Newman, T.A., Galea, I., Van Rooijen, N., Perry, V.H. , 2005. Blood-derived dendritic cells in an acute brain injury. J. Neuroimmunol.. vol. 166. pp. 167-172. (#330)



• Fukushima, A., Ozaki, A., Ishida, W., Van Rooijen, N., Fukata, K., Ueno, H., 2005. Suppression of macrophage infiltration into the conjunctiva by clodronate liposomes in experimental immune-mediated blepharoconjunctivitis. Cell Biol. Int. . vol. 29. pp. 277-286. (#329)



• Nierkens, S., Bleumink, R., Bol, M., Hassing, I., Van Rooijen, N., Pieters, R. , 2005. The Reactive d-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8(+) T cells. Chem. Res. Toxicol. . vol. 18. pp. 872-879. (#328)



• Ezendam, J., Kosterman, K., Spijkerboer, H., Bleumink, R., Hassing, I., Van Rooijen, N., Vos, J.G., Pieters, R., 2005. Macrophages are involved in hexachlorobenzene-induced adverse immune effects. Tox. Appl. Pharmacol. . vol. 209. pp. 19-27. (#327)



• Machemer, T., Engler, H., Tsai, V., Lee, S., Cannon-Carlson, S., Voloch, M., Schluep, T., Ravindran, S., Vellekamp, G., Brin, E., Cornell, D., Sutjipto, S., Fen Wen, S., Horn, M., Van Rooijen, N., Maneval, D., Hutchins, B., LaFace, D. , 2005. Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses. Mol. Ther.. vol. 12. pp. 254-263. (#326)



• Bustuoabad, O.D., Ruggiero, R.A., Di Gianni, P., Lombardi, M.G., Belli, C., Camerano, G.V., Dran, G., Schere-Levy, C., Costa, H., Isturiz, M.A., Narvaitz, M., Van Rooijen, N., Bustuoabad, V. de L., Meiss, R.P. , 2005. Tumor transition zone: a putative new morphological and functional hallmark of tumor aggressiveness. Oncol. Res.. vol. 15. pp. 169-182. (#325)



• Stamatovic, S.M., Shakui, P., Keep, R.F., Moore, B.B., Kunkel, S.L., Van Rooijen, N., Andjelkovic, A.V., 2005. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability . J. Cereb. Blood Flow Metab. . vol. 25. pp. 593-606. (#324)



• Skokowa, J., Ali, S.R., Felda, O., Kumar, V., Konrad, S., Shushakova, N., Schmidt, R.E., Piekorz, R.P., Nurnberg, B., Spicher, K., Birnbaumer, L., Zwirner,, J., Claassens, J.W.C., Verbeek, J.S., van Rooijen, N., Kohl, J., Gessner, J.E. , 2005. Macrophages induce the inflammatory response in the pulmonary Arthus reaction through Galphai2 activation that controls C5aR and Fc receptor cooperation. J. Immunol.. vol. 174. pp. 3041 - 3050. (#323)



• Lou, D.Q., Lesbordes, J.C., Nicolas, G., Viatte. L., Bennoun, M., Van Rooijen, N., Kahn, A., Renia, L., Vaulont, S., 2005. Iron- and inflammation-induced hepcidin gene expression is not mediated by Kupffer cells in vivo. Hepatology. vol. 41. pp. 1056-1064. (#322)



• Schmieg, J., Yang, G., Franck,R.W., Van Rooijen, N., Tsuji, M., 2005. Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion . Proc. Natl. Acad. Sci. U S A. vol. 102. pp. 1127-1132. (#320)



• Nemmar, A., Nemery, B., Hoet, P.H.M., Van Rooijen, N., Hoylaerts, M.F., 2005. Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk . Am. J. Respir. Crit. Care Med. . vol. 171. pp. 872-879. (#319)



• Tribulatti, M.V., Mucci, J., Van Rooijen, N., Leguizamon, M.S., Campetella, O., 2005. The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas’ disease by reducing the platelet sialic acid contents. Infect. Immun.. vol. 73. pp. 201-207. (#318)



• Geier, A., Zollner, G., Dietrich, C.G., Wagner, M., Fickert, P., Denk, H., Van Rooijen, N., Matern, S., Gartung, C., Trauner, M., 2005. Cytokine-independent repression of rodent Ntcp in obstructive cholestasis. Hepatology. vol. 41. pp. 470-477. (#316)



• Leemans, J.C., Thepen, T., Weijer, S., Florquin, S., Van Rooijen, N., Van de Winkel, J.G., Van der Poll, T. , 2005. Macrophages play a dual role during pulmonary tuberculosis in mice. J. Infect. Dis. vol. 191. pp. 65-74. (#315)



• Nikolic, T., Geutskens, S.B., Van Rooijen, N., Drexhage, H.A., Leenen, P.J.M. , 2005. Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the non-obese diabetic mouse: A phagocyte depletion study. Laboratory investigation. vol. 85. pp. 487-501. (#314)



• Sturm, E., Havinga, R., Baller, J.F.W., Wolters, H., Van Rooijen, N., Kamps, J.A.A.M., Verkade, H.J., Karpen, S.J., Kuipers, F. , 2005. Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats. J. Hepatol.. vol. 42. pp. 102-109. (#313)



• Garzon, R.M., Berraondo, P., Crettaz, J., Ochoa, L., Vera, M., Lasarte, J.J., Vales, A., Van Rooijen, N., Ruiz, J., Prieto, J., Zulueta, J., Gonzalez-Aseguinolaza, G. , 2005. Induction of gp 120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex. Vaccine. vol. 23. pp. 1384-1392. (#312)



• Moreno,S.A., Moreno, M., Moreno,F.J., Eguiluz, C., Van Rooijen, N., Benito, A. , 2005. Experimental infection of immunomodulated NOD/LtSz-SCID mice as a new model for Plasmodium falciparum erythrocytic stages. Parasitol. Res.. vol. 95. pp. 97-105. (#311)



• Kotter, M.R., Zhao, C., Van Rooijen, N., Franklin, R.J.M., 2005. Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol. Dis. . vol. 18. pp. 166-175. (#310)



• Galea, I., Newman, T., Palin, K., Van Rooijen, N., Perry, V.H., Boche, D., 2005. Mannose receptor expression specifically reveals perivascular macrophages in normal, injured and diseased mouse brain. Glia. vol. 49. pp. 375-384. (#301)

2004:

• Chadzinska, M., Kolaczkowska, E., Scislowska-Czarnecka, A., Van Rooijen, N., Plytycz, B. , 2004. Effects of macrophage depletion on peritoneal inflammation in swiss mice, edible frogs and goldfish. Folia Biologica (Krakow). vol. 52. pp. 225-231. (#321)



• Landoni, V.I., Vermeulen, M., Van Rooijen, N., Gomex, S., Palermo, M., Isturiz, M.A., Alves-Rosa, F., 2004. Macrophage derived signalling regulates negatively the megakaryocyte compartment. Cell Mol. Biol. . vol. 50. pp. OL667-OL675. (#317)



• Mangan, N.E., Fallon, R.E., Smith, P., Van Rooijen, N., McKenzie, A.N., Fallon, P.G. , 2004. Helminth infection protects mice from anaphylaxis via IL-10 producing B cells. J. Immunol.. vol. 173. pp. 6346-6356. (#309)



• Cote, C.K., Rea, K.M., Norris, S.L., Van Rooijen, N., Welkos, S.L. , 2004. The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores. Microb. Pathog. . vol. 37. pp. 169-175. (#308)



• Qu, C., Edwards, E.W., Tacke, F., Angeli, V., Llodra, J., Sanchez-Schmitz, G., Garin, A., Haque, N.S., Peters, W., Van Rooijen, N., Sanchez-Torres, C., Bromberg, J., Charo, I.F., Jung, S., Lira, S.A., Randolph, G.J. , 2004. Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J. Exp. Med.. vol. 200. pp. 1231-1241. (#307)



• Jiang, Z., Schiedner, G., Van Rooijen, N., Liu, C.C., Kochanek, S., Clemens, P.R., 2004. Sustained muscle expression of dystrophin from a high-capacity adenoviral vector with systemic gene transfer of T cell costimulatory blockade. Mol. Ther.. vol. 10. pp. 688-696. (#306)



• Godau, J., Heller, T., Hawlisch, H., Trappe, M., Howells, E., Best, J., Zwirner, J., Verbeek, J.S., Hogarth, P.M., Gerard, C., Van Rooijen, N., Klos, A., Gessner, J.E., Kohl, J. , 2004. C5a initiates the inflammatory cascade in immune complex peritonitis. J. Immunol.. vol. 173. pp. 3437-3445. (#305)



• Sammels, L.M., Bosio, E., Fragall, C.T., Grounds, M.D., Van Rooijen, N., Beilharz, M.W., 2004. Innate inflammatory cells are not responsible for early death of donor myoblasts after myoblast transfer therapy. . Transplantation. vol. 77. pp. 1790-1797. (#304)



• Murphy, E.A., Davis, J.M., Brown,A.S., Carmichael, M.D., Van Rooijen, N., Chaffar, A., Mayer, E.P., 2004. Role of lung macrophages on susceptibility to respiratory infection following short-term moderate exercise training. Am. J. Physiol.. vol. 287. pp. R1354-1358. (#303)



• Blom, A.B., Van Lent, P.L., Holthuysen, A.E., Van Der Kraan, P.M., Roth, J., Van Rooijen, N., Van Der Berg, W.B. , 2004. Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. Osteoarthritis Cartilage. vol. 12. pp. 627-635. (#302)



• Chen, Y., Lui, V.C.H., Van Rooijen, N., Tam, P.K.H., 2004. Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut. Gut. vol. 53. pp. 1772-1780. (#300)



• Gao, H., Guo, R.F., Speyer, C.L., Reuben, J., Neff, T.A., Hoesel, L.M., Riedemann, N.C., McClintock, S.D., Sarma, J.V., Van Rooijen, N., Zetoune, F.S., Ward, P.A., 2004. Stat3 activation in acute lung injury. J. Immunol.. vol. 172. pp. 7703-7712. (#299)



• Hughes, E.H., Schlichtenbrede , F.C., Murphy, C.C., Broderick, C., Van Rooijen, N., Ali, R.R., Dick, A.D., 2004. Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism. Exp. Eye Res.. vol. 78. pp. 1077-1084. (#298)



• Silva, G.C., Nagib, P.R.A., Chiari, E., Van Rooijen, N., Machado, C.R.S., Camargos, E.R.S., 2004. Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi – infected suckling rats. J. Neuroimmunol.. vol. 149. pp. 50-58. (#297)



• Sunderkotter, C., Nikolic, T., Dillon, M.J., Van Rooijen, N., Stehling, M., Drevets, D.A., Leenen, P.J.M. , 2004. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J. Immunol.. vol. 172. pp. 4410-4417. (#296)



• Drevets, D.A., Dillon, M.J., Schawang, J.S., Van Rooijen, N., Ehrchen, J., Sundercotter, C., Leenen, P.J.M., 2004. The Ly-6C high monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice. J. Immunol.. vol. 172. pp. 4418-4424. (#295)



• Wolff, R.A., Tomas, J.T., Hullett, D.A., Stark, V.E., Van Rooijen, N., Hoch, J.R. , 2004. Macrophage depletion reduces monocyte chemotactic protein-1 and transforming growth factor-beta-1 in healing rat vein grafts. J. Vasc. Surg.. vol. 39. pp. 878-888. (#294)



• Lee, A.M., Fryer, A.D., Van Rooijen, N., Jacoby, D.B., 2004. The role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction. Am. J. Physiol.. vol. 286. pp. L1255-1259. (#293)



• Marin-Teva, J.L., Dusart, I., Colin, C., Gervais, A., Van Rooijen, N., Mallat, M. , 2004. Microglia promote the death of developing Purkinje cells. Neuron. vol. 41. pp. 535-547. (#292)



• Slegers, T.P.A.M., Broersma, L., Van Rooijen, N., Hooymans, J.M.M., Van Rij, G., Van der Gaag, R. , 2004. Macrophages play a role in the early phase of corneal allograft rejection in rats. Transplantation. vol. 77. pp. 1641-1646. (#291)



• Muhlen, K.A., Schumann, J., Wittke, F., Stenger, S., Van Rooijen, N., Van Kaer, L., Tiegs, G., 2004. NK cells but not NKT cells are involved in Pseudomonas aeruginosa exotoxin A - induced hepatoxicity in mice. J. Immunol.. vol. 172. pp. 3034-3041. (#290)



• Jasinski, M., Pantazopoulos, P., Rother, R.P., Van Rooijen, N., Song, W.C., Molina, H., Bessler, M. , 2004. A novel mechanism of complement independent clearance of red cells deficient in glycosyl phosphatidylinositol linked proteins. Blood. vol. 103. pp. 2827-2834. (#289)



• Van Lent, P.L.E.M., Blom, A.B.,Van der Kraan, P., Holthuyzen, A.E.M., Vitters, E., Van Rooijen, N., Smeets, R.L., Nabbe, K.C.A.M., Van den Berg, W.B. , 2004. Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. Arthritis Rheum.. vol. 50. pp. 103-111. (#286)

2003:

• Schiedner, G., Bloch, W., Hertel, S., John,M., Molojavyi, A., Dries, V., Varga, G., Van Rooijen, N., Kochanek, S. , 2003. A hemodynamic response to intravenous adenovirus vector particles is caused by systemic kupffer cell-mediated activation of endothelial cells. Human Gene Therapy. vol. 14. pp. 1631-1641. (#288)



• Stager, S., Alexander, J., Kirby, A.C., Botto, M., Van Rooijen, N., Smith, D.F., Brombacher, F., Kaye, P.M. , 2003. Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. Nature Medicine. vol. 9. pp. 1287-1292. (#287)



• Emoto, M., Miyamoto, M., Emoto, Y., Yoshizawa, I., Brinkmann, V., Van Rooijen, N., Kaufmann, S.H.E. , 2003. Highly biased type-1-immune responses in mice deficient in LFA-1 in Listeria monocytogenes infection are caused by elevated IL-12 production by granulocytes. . J. Immunol.. vol. 171. pp. 3970-3976. (#285)



• Saeij, J.P.J., Groeneveld, A., Van Rooijen, N., Haenen, O.L.M., Wiegertjes, G.F. , 2003. Minor effect of depletion of resident macrophages from peritoneal cavity on resistance of common carp Cyprinus carpio to blood flagellates. Dis. Aquat. Organ. . vol. 57. pp. 67-75. (#284)



• Jose, M.D., Ikezumi, Y., Van Rooijen, N., Atkins, R.C., Chadban, S.J. , 2003. Macrophages act as effectors of tissue damage in acute renal allograft rejection. Transplantation. vol. 76. pp. 1015-1022. (#283)



• Naidu, B.V., Krishnadasan, B., Farivar, A.S., Woolley,S.M., Thomas, R., Van Rooijen, N., Verrier, E.D., Mulligan, M.S. , 2003. Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury. J. Thorac. Cardiovasc. Surg. . vol. 126. pp. 200-207. (#282)



• Van Rooijen, N., Van Kesteren-Hendrikx, E., 2003. "In vivo" depletion of macrophages by liposome-mediated "suicide".. Methods in Enzymology. vol. 373. pp. 3-16. (#281)



• Nolte, M.A., Belien, J.A.M., Schadee-Eestermans, I., Jansen,W., Unger, W.W.J., Van Rooijen, N., Kraal, G., Mebius, R.E. , 2003. A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp. J. Exp. Med.. vol. 198. pp. 505-512. (#280)



• Emoto, M.,Emoto, Y., Brinkmann, V., Miyamoto, M.,Yoshizawa, I., Staber, M. Van Rooijen, N., Hamann, A., Kaufmann, S.H.E., 2003. Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: A novel role for LFA-1 in the regulation of the pro-inflammatory and anti-inflammatory cytokine balance.. J. Immunol.. vol. 171. pp. 584-593. (#279)



• Sakurai, E., Anand, A., Ambati, B.K., Van Rooijen, N., Ambati, J. , 2003. Macrophage depletion inhibits experimental choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. . vol. 44. pp. 3578-3585. (#278)



• Masztalerz, A., Van Rooijen, N., Den Otter, W., Everse, L.A. , 2003. Mechanism of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression. Cancer Immunol. Immunother. . vol. 52. pp. 235-242. (#277)



• Sheikh, N.A., Attard, G.S., Van Rooijen, N., Rajananthanan, P., Hariharan, H., Yang, Y.W, Morrow, W.J.W., 2003. Differential requirements for CTL generation by novel immunostimulants: APC tropism, use of the TAP independent processing pathway and dependency on CD80/CD86 costimulation . Vaccine. vol. 21. pp. 3775-3788. (#276)



• McClellan, S.A., Huang, X., Barrett, R.P., Van Rooijen, N., Hazlett, L.D. , 2003. Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx and balance pro- and anti-inflammatory cytokines in BALB/c mice. J. Immunol. . vol. 170. pp. 5219-5227. (#275)



• Slegers, T.P.A.M., Van der Veen, G., Hermans, L.J.A., Broersma, L., Van Rooijen, N.,Volker-Dieben, H.J., Van Rij, G., Van der Gaag, R., 2003. Adhesion molecule expression in local macrophage depleted rats bearing orthotopic corneal allografts. Graef. Arch. Clin. Exp. Ophthalmol. . vol. 241. pp. 432-438. (#274)



• Belnoue, E., Costa, F. T. M., Vigario, A.M., Voza, T., Gonnet, F., Landau, I., Van Rooijen, N., Mack, M., Kuziel, W.A., Renia, L, 2003. Chemokine Receptor CCR2 is not essential for the development of experimental cerebral malaria. Infect. Immun. . vol. 71. pp. 3648-3651. (#273)



• Kraal, G., Van Rooijen, N, 2003. Reaching the macrophage: Routes of delivery. In “The macrophage as therapeutic target”.. Handbook of Experimental Pharmacology. vol. 158. pp. 55-65. (#272)



• Rivas, C., Djeraba, A., Musset, E., Van Rooijen, N., Baaten, B., Quere, P., 2003. Intravenous treatment with liposome-encapsulated dichloromethylene bisphosphonate (Cl2MBP) suppresses nitric oxide production and reduces genetic resistance to Marek’s disease. Avian Pathology. vol. 32. pp. 139-149. (#271)



• Schiedner, G., Hertel, S., Johnston, M., Dries, V., Van Rooijen, N., Kochanek, S. , 2003. Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors.. Mol. Ther.. vol. 7. pp. 35-43. (#270)



• Selzner, N., Selzner, M., Odermatt, B., Tian, Y., Van Rooijen, N., Clavien, P.-A. , 2003. ICAM 1 triggers liver regeneration through leukocyte recruitment and Kupffer cell dependent release of TNF-alpha/IL-6 in mice.. Gastroenterology. vol. 124. pp. 692-700. (#269)



• Popovich, P.G., van Rooijen, N., Hickey, W.F., Preidis, G., McGaughy, V. , 2003. Hematogenous macrophages express CD8 and distribute to regions of lesion cavitation after spinal cord injury.. Exp. Neurol.. vol. 182. pp. 275-287. (#268)