Publications

1993:

• Van Lent,P.L.E.M., Van De Hoek,A., Van Den Bersselaar,L., Spanjaards, M.F.R.,Van Rooijen,N., Dijkstra,C.D., Van De Putte, L.B.A. and Van Den Berg, W.B., 1993. In vivo role of phagocytic synovial lining cells in onset of experimental arthritis. Am. J. Pathol.. vol. 143. pp. 1226-1237. (#65)



• Van Lent, P.L.E.M., Van Den Bersselaar, L., Van Den Hoek, A.E.M., Van De Ende, M., Dijkstra,C.D., Van Rooijen,N., Van De Putte, L.B.A. and Van Den Berg, W.B., 1993. Reversible depletion of synovial lining cells after intraarticular treatment with liposome encapsulated dichloromethylene diphosphonate. Rheumat.Intern.. vol. 13. pp. 21-30. (#64)



• Vreden,S.G.S., Sauerwein,R.W., Verhave,J.P., Van Rooijen,N., Meuwissen, J.H.E.T. and Van Den Broek,M.F., 1993. Kupffer cell elimination enhances the development of liver Schizonts of Plasmodium Berghei in rats. Infect. Immunity. vol. 61. pp. 1936-1939. (#63)



• Han,Y.,Van Rooijen,N. and Cutler,J.E., 1993. Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages. Infect. Immunity. vol. 61. pp. 3244-3249. (#62)



• Huppes,W.,Paulonis,J.,Dijk,H., Van Rooijen,N. and Van Bekkum,D.W., 1993. The role of natural antibodies and ABO(H) blood groups in transplanta- tion of human lymphoid cells into mice. Eur. J. Immunol.. vol. 23. pp. 26-32. (#61)



• Heuff,G.,Boutkan,H.,Beelen,R.H.J.,Van Rooijen,N.,Meyer,S. and Dijkstra, C.D., 1993. Kinetics and functional role of Kupffer cells in controlling hepatic metastasis. In "Cells of the hepatic sinusoid"(Knook D.L. and Wisse,E. eds.). vol. 4. pp. 500-503. (#60)



• Heuff,G., Oldenburg,H.S.A., Boutkan,H., Visser,J.J., Beelen,R.H.J., Van Rooijen,N., Dijkstra,C.D. and Meyer,S., 1993. Enhanced tumour growth in the rat liver after selective elimination of Kupffer cells. Cancer Immunol. Immunother. . vol. 37. pp. 125-130. (#59)



• Coremans,I.E.M., Bogers,W.M.J.M.,Stad,R.K., Van der Voort,E.A.M.,Prins, F.A.,Van Rooijen,N.,Breedveld,F.C. and Daha,M.R., 1993. Role of liver endothelial and Kupffer cells in clearance of human C1q in rats. Eur. J. Immunol.. vol. 23. pp. 1942-1947. (#58)



• Bogers, W.M.J.M., Van Rooijen, N., Janssen, D.J.,Van Es, L.A. and Daha, M.R., 1993. Complement enhances the elimination of soluble aggregates of IgG by rat liver endothelial cells in vivo. Eur. J. Immunol.. vol. 23. pp. 433-438. (#57)



• Bette,M.,Schafer,M.K.H.,Van Rooijen,N.,Weihe,E. and Fleischer,B., 1993. Distribution and kinetics of superantigen-induced cytokine gene expression in mouse spleen. J. Exp. Med.. vol. 178. pp. 1531-1540. (#56)



• Berkenbosch,F.,Van Rooijen,N. and Tilders,F.J.H., 1993. Determining role and sources of endogenous interleukin-1 in pituitary-adrenal activation in response to stressful and inflammatory stimuli. In: "Methods in Neurosciences": Neurobiology of cytokines, Part A (De Souza,E.B. Ed.). vol. 16. pp. 211-231. (#55)



• Bergh, A., Damber, J-E, and Van Rooijen, N., 1993. The HCG-induced inflammation-like response is enhanced in macrophage-depleted testes. J. Endocrinol.. vol. 136. pp. 415-420. (#54)



• Bergh, A., Damber, J-E, and Van Rooijen, N., 1993. Liposome-mediated macrophage depletion: An experimental approach to study the role of testicular macrophages. J. Endocrinol.. vol. 136. pp. 407-413. (#53)



• Van Rooijen, N., 1993. Immunoadjuvant activities of liposomes: Two different macrophage mediated mechanisms. Vaccine. vol. 11. pp. 1170. (#52)



• Van Rooijen, N., 1993. Extracellular and intracellular action of clodronate in osteolytic bone diseases: A hypothesis. Calcified Tiss. Internat.. vol. 52. pp. 407-410. (#51)

1992:

• Buiting, A.M.J., Van Rooijen,N. and Claassen,E., 1992. Liposomes as antigen carriers and adjuvants "in vivo" In: 44th Forum in Immunology . Res. Immunol.. vol. 143. pp. 541-548. (#50)



• Huitinga,I.,Damoiseaux,J.G.M.C.,Van Rooijen.N., Dopp,E.A. and Dijkstra, C.D., 1992. Liposome mediated affection of monocytes. Immunobiology. vol. 185. pp. 11-19. (#49)



• Van Lent, P.L.E.M., Van den Hoek,A., Van den Bersselaar, Dijkstra,C.D., Van Rooijen,N. and Van den Berg W.B., 1992. Role of synovial macrophages in experimental arthritis. In: 41st Forum in Immunology . Res. Immunol.. vol. 143. pp. 229-234. (#48)



• De Rijk, R.H., Van Rooijen,N. and Berkenbosch,F., 1992. The role of macrophages in the hypothalamic-pituitary-adrenal activation in response to endotoxin (LPS)In: 41st Forum in Immunology . Res. Immunol.. vol. 143. pp. 224-229. (#47)



• Van Rooijen, N. and Poppema, A., 1992. Efficacy of various water soluble chelator molecules in the liposome mediated macrophage "suicide" technique. J. Pharmacol. Meth.. vol. 28. pp. 217-221. (#46)



• Van Rooijen, N., 1992. Liposomes. In: Encyclopedia of Immunology. Eds. I.M. Roitt and P.J. Delves. W.B. Saunders Company. pp. 986-988. (#45)



• Van Rooijen, N., 1992. Liposome-mediated elimination of macrophages In 41st Forum in Immunology: Liposomes as an "in vivo" tool to study and manipulate macrophage function.. Res. Immunol.. vol. 143. pp. 215-219. (#44)



• Van Rooijen, N., 1992. Liposomes as an "in vivo" tool to study and manipulate macrophage function: Introduction 41st Forum in Immunology.. Res. Immunol.. vol. 143. pp. 177-178. (#43)



• Van Rooijen, N., 1992. Macrophages as accessory cells in the "in vivo" humoral immune response: From processing of particulate antigens to regulation by suppression. Semin. Immunol.. vol. 4 . pp. 237-245. (#42)

1991:

• Soesatyo,M., Biewenga,J., Van Rooijen,N., Kors,N., and Sminia,T., 1991. The "in situ" immune response of the rat after intraperitoneal depletion of macrophages by liposome-encapsulated dichloromethylene diphosphonate. Res. Immunol.. vol. 142. pp. 533-540. (#41)



• Monkkonen,J., Van Rooijen,N. and Ylitalo,P., 1991. Effects of clodronate and pamidronate on splenic and hepatic phagocytic cells of mice. Pharmacol. Toxicol.. vol. 68. pp. 284-286. (#40)



• Pinto,A.J., Stewart,D., Van Rooijen,N. and Morahan,P.S., 1991. Selective depletion of liver and splenic macrophages using liposomes encapsulating the drug dichloromethylene diphosphonate: Effects on antimicrobial resistance. J. Leuk. Biol.. vol. 49. pp. 579-586. (#39)



• Delemarre,F.G.A., Kors,N., and Van Rooijen,N., 1991. The role of the spleen and of lymph node macrophages in the immune response to particulate antigens. In " Lymphatic tissues and in vivo immune responses".(Imhof et al.eds.) Marcel Dekker,Inc. New York. pp. 843-847 (chapter 145). (#38)



• Delemarre,F.G.A., Kors,N. and Van Rooijen,N., 1991. Elimination of spleen and of lymph node macrophages and its difference in the effect on the immune response to particulate antigens. Immunobiology. vol. 182. pp. 70-78. (#37)



• De Rijk, R., Van Rooijen,N., Tilders, F., Besedovsky, H., Del Rey, A., and Berkenbosch, F., 1991. Selective depletion of macrophages prevents increased plasma interleukin-1 concentrations and pituitary-adrenal activation in response to endotoxin administration in rats. Endocrinology. vol. 129. pp. 330-338. (#36)



• Bogers, W.M.J.M., Stad,R.K., Janssen,D.J., Van Rooijen,N.,Van Es, L.A., Daha,M.R., 1991. Kupffer cell depletion "in vivo" results in preferential elimination of IgG aggregates and immune complexes via specific Fc receptors on rat liver endothelial cells. Clin. Exp. Immunol.. vol. 86. pp. 328-333. (#35)



• Bogers, W.M.J.M., Stad, R.K., Janssen, D.J., Prins, F.A., Van Rooijen, N., Van Es, L.A., and Daha, M.R., 1991. Kupffer cell depletion in vivo results in clearance of large sized IgA aggregates in rats by liver endothelial cells. Clin. Exp. Immunol.. vol. 85. pp. 128-136. (#34)



• Van Rooijen, N., 1991. High and low cytosolic Ca2+ induced macrophage death ?. Cell Calcium. vol. 12. pp. 381-384. (#33)

1990:

• Claassen, I., Van Rooijen, N., and Claassen, E., 1990. A new method for removal of mononuclear phagocytes from heterogenous cell populations 'in vitro', using the liposome-mediated macrophage 'suicide' technique. J. Immunol. Meth.. vol. 134. pp. 153-161. (#32)



• Huitinga, I., Van Rooijen, N., De Groot, C.J.A., Uitdehaag, B.M.J., and Dijkstra, C.D., 1990. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med.. vol. 172. pp. 1025-1033. (#31)



• Huitinga, I., Van Rooijen, N., De Groot, C.J.A., Uitdehaag, B.M.J., and Dijkstra, C.D., 1990. Elimination of macrophages infiltrating into the Central Nervous System suppresses experimental allergic encephalomyelitis in Lewis rats. Ann. N.Y. Acad. Sci.. vol. 594. pp. 458-460. (#30)



• Delemarre, F.G.A., Kors, N., Van Rooijen, N., 1990. The 'in situ' immune response in popliteal lymph nodes of mice after macrophage depletion. Differential effects of macrophages on thymus-dependent and thymus- independent immune responses.. Immunobiology. vol. 180. pp. 395-404. (#29)



• Delemarre, F.G.A., Kors, N., Kraal, G., Van Rooijen, N., 1990. Repopulation of macrophages in popliteal lymph nodes of mice after liposome mediated depletion. J. Leuk. Biol.. vol. 47. pp. 251-257. (#28)



• Laman, J.D., Kors, N., Van Rooijen, N., and Claassen, E., 1990. Mechanisms of follicular trapping: Localisation of immune complexes and cell remnants after elimination and repopulation of different spleen cell populations. Immunology. vol. 71. pp. 57-62. (#27)



• Van Rooijen, N., Kors, N., Van den Ende, M., Dijkstra, C.D., 1990. Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome encapsulated dichloromethylene diphosphonate. Cell Tissue Res.. vol. 260. pp. 215-222. (#26)



• Van Rooijen, N., 1990. Antigen processing and presentation in vivo: The microenvironment as a crucial factor. Immunol. Today. vol. 11. pp. 436-439. (#25)



• Van Rooijen, N., 1990. Liposomes as carrier and immunoadjuvant of vaccine antigens. In: Bacterial vaccines. Ed. A. Mizrahi. Alan R. Liss, N.Y. USA. Adv. Biotechnol. Processes. vol. 13. pp. 255-279. (#24)

1989:

• Bleeker, W.K., Agterberg, J., Rigter, G., Van Rooijen, N., Bakker, J.C., 1989. Key role of macrophages in hypotensive side effects of immunoglobulin preparations. Studies in an animal model.. Clin. Exp. Immunol.. vol. 77. pp. 338-344. (#23)



• Kraal, G., Rodriques, H., Hoeben, K., Van Rooijen, N., 1989. Lymphocyte migration in the spleen: The effect of macrophage elimination on lymphocyte distribution. Immunology. vol. 68. pp. 227-232. (#22)



• Pinto, A.J., Stewart, D., Volkman, A., Jendrasiak, G., Van Rooijen, N., Morahan, P.S., 1989. Selective depletion of macrophages using toxins encapsulated in liposomes: Effect on antimicrobial resistance. In: Liposomes in the therapy of infectious diseases and cancer. Eds. G. Lopez-Berestein, I. Fidler. Alan R. Liss, N.Y. USA. pp. 441-451. (#21)



• Thepen, T., Van Rooijen, N., Kraal, G., 1989. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune responses in mice. J. Exp. Med.. vol. 170. pp. 499-509. (#20)



• Su, D., Van Rooijen, N., 1989. The role of macrophages in the immunoadjuvant action of liposomes: Effects of elimination of splenic macrophages on the immune response against intravenously injected liposome associated albumin antigen. Immunology. vol. 66. pp. 466-470. (#19)



• Van Rooijen, N., 1989. The liposome mediated macrophage 'suicide' technique. J. Immunol. Meth.. vol. 124. pp. 1-6. (#18)



• Van Rooijen, N., Su, D., 1989. Immunoadjuvant action of liposomes: Mechanisms. In: Immunological adjuvants and vaccines. NATO ASI Series A. Ed. G. Gregoriadis. Plenum Publ. Comp. USA. vol. 179. pp. 95-106. (#17)



• Van Rooijen, N., Claassen, E., Kraal, G., Dijkstra, C.D., 1989. Cytological basis of immune functions in the spleen: Immunocytochemical characterization of lymphoid and non-lymphoid cells involved in the 'in situ' immune response. Progr. Histochem. Cytochem.. vol. 19 (No. 3). pp. 1-71. (#16)



• Van Rooijen, N., Kors, N., 1989. Effects of intracellular diphosphonates on cells of the mononuclear phagocyte system. In vivo effects of liposome encapsulated diphosphonates on different macrophage subpopulations in the spleen.. Calcified Tiss. Internat.. vol. 45. pp. 153-156. (#15)



• Van Rooijen, N., Kors, N., Kraal, G., 1989. Macrophage subset repopulation in the spleen: Differential kinetics after liposome- mediated elimination. J. Leuk. Biol.. vol. 45. pp. 97-104. (#14)

1988:

• Claassen, E., Westerhof, Y., Versluis, B., Kors, N., Schellekens, M., Van Rooijen, N., 1988. Effects of chronic injection of sphingomyelin containing liposomes on lymphoid and non-lymphoid cells in the spleen. Transient suppression of marginal zone macrophages.. Br. J. Exp. Pathol.. vol. 69. pp. 865-875. (#13)



• Groeneveld, P.H.P., Claassen, E., Kuper, C.F., Van Rooijen, N., 1988. The role of macrophages in LPS-induced lethality and tissue injury. Immunology. vol. 63. pp. 521-527. (#12)



• Van Rooijen, N., Kors, N., Kraal, G., 1988. Characterization of cell populations reappearing in the mouse spleen after elimination by liposome encapsulated dichloromethylene diphosphonate: Reappearance of marginal zone lymphocytes is independent of marginal zone macrophages. Adv. Exp. Med. Biol.. vol. 237. pp. 901-905. (#11)



• Van Rooijen, N., Claassen, E., 1988. In vivo elimination of macrophages in spleen and liver, using liposome encapsulated drugs: Methods and applications. In: Liposomes as drug carriers: Trends and progress. Ed. G. Gregoriadis. John Wiley and Sons, Chichester, U.K.. pp. 131-143 (chapter 9). (#10)



• Van Rooijen, N., 1988. Liposomes as immunological adjuvants: Recent developments. In: Liposomes as drug carriers: Trends and progress. Ed. G. Gregoriadis. John Wiley and Sons, Chichester, U.K.. pp. 159-165 (chapter 11). (#9)

1987:

• Claassen,E., Kors,N. and Van Rooijen,N., 1987. Immunomodulation with liposomes: The immune response elicited by liposomes with entrapped dichloromethylene-diphosphonate and surface associated antigen or hapten. Immunology. vol. 60. pp. 509-515. (#8)



• Van Rooijen,N., Kors,N., Ter Hart,H. and Claassen,E., 1987. In vitro and In vivo elimination of macrophage tumor cells using liposome- encapsulated dichloromethylene-diphosphonate. Virchows Arch. B (Cell Pathol.). vol. 54. pp. 241-245. (#7)

1986:

• Claassen,E. and Van Rooijen,N., 1986. Preparation and characteristics of dichloromethylene-diphosphonate containing liposomes. J. Microencapsul.. vol. 3. pp. 109-114. (#6)



• Claassen,E., Kors,N. and Van Rooijen,N., 1986. Influence of carriers on the development and localization of anti-2,4,6-trinitrophenyl (TNP) antibody forming cells in the murine spleen. II. Suppressed antibody response to TNP-Ficoll after elimination of marginal zone cells.. Eur. J. Immunol.. vol. 16. pp. 492-497. (#5)

1985:

• Claassen,E. and Van Rooijen,N., 1985. Evidence that macrophages in the marginal zone have no role in the migration of lymphocytes into the periarteriolar lymphocyte sheaths (PALS). Immunology. vol. 56. pp. 689-694. (#4)



• Van Rooijen,N., Van Nieuwmegen,R. and Kamperdijk, E. W. A., 1985. Elimination of phagocytic cells in the spleen after intravenous injection of liposome encapsulated dichloromethylene diphosphonate. Ultrastructural aspects of elimination of marginal zone macrophages.. Virchows Arch. B (Cell Pathol.). vol. 49. pp. 375-383. (#3)

1984:

• Claassen,E. and Van Rooijen,N., 1984. The effect of elimination of macrophages on the tissue distribution of liposomes containing 3H- methotrexate. Bioch. Bioph. Acta. vol. 802. pp. 428-434. (#2)



• Van Rooijen,N. and Van Nieuwmegen,R., 1984. Elimination of phagocytic cells in the spleen after intravenous injection of liposome encapsulated dichloromethylene-diphosphonate. An enzyme-histochemical study.. Cell Tissue Res.. vol. 238. pp. 355-358. (#1)